Hae
Aineistot 61-70 / 576
Novel genes and regulatory systems in epididymal differentiation and sperm maturation of the mouse.
(Annales Universitatis Turkuensis D 1151Turun yliopisto, 2014-12-12)
Mammalian spermatozoa gain their fertilizing ability during maturation in the epididymis. Proteins and lipids secreted into the epididymal lumen remodel the sperm membrane, thereby providing the structure necessary for ...
Imaging and target screening for novel avenues for psychiatric disorder treatments
(2020-02-18)
The JNK pathway is linked to both schizophrenia and depression but its impact is still being investigated. Zebrafish larvae at 7 days post-fertilization, were monitored for evoked motility changes after exposure to a variety ...
Securin-related cell proliferation in breast cancer prognosis
(Turun yliopisto, 2020-03-13)
Breast cancer is the most common malignancy among women. It remains a major cause of mortality among women, although the five-year survival of breast cancer patients is about 90%. To aid in the clinical treatment decisions, ...
Regulation of Spermatogenesis: Differentiation of GFP-labeled Stem Cells and the Function of Cytoplasmic Bridges
(Turun yliopisto, 2003)
During spermatogenesis, different genes are expressed in a strictly coordinated fashion providing an excellent model to study cell differentiation. Recent identification of testis specific genes and the development of green ...
The role of the GABAA receptor δ subunit domains on agonist binding kinetics
(2019-11-27)
The GABAA receptor is a ligand-gated ion channel that conveys inhibitory signals in neurons. It is a pentameric receptor assembled from combinations of 19 subunits, however, most receptors are composed of α-, β- and ...
Mechanistic study of JNK inhibition in the context of depression
(2019-10-10)
Study 1:
Anxiety and depression disorders are the largest contributor for global disability and affects 4% of the world population. The patient remission rate is only 30-40% with single anti-depressant treatment, leaving ...
Opioidisalpaaja naloksonin annostelu nenäsuihkeena : Farmakologia ja kliiniset käyttömahdollisuudet
(Turun yliopisto, 2018-04-18)
ANDROGEN SIGNALING AXIS AS DRUG TARGET IN CASTRATION-RESISTANT PROSTATE CANCER: Preclinical development of novel treatments and models
(Turun yliopisto, 2018-06-15)
Abstract:
Prostate cancer is a major global challenge due to the increasing number of aging population
and frequency of diagnosis. Already in 1941, Huggins and Hodges showed that metastatic
prostate cancer is responsive ...
Verenkierto, hengitys ja nestetasapaino -kurssin oppimateriaalityö : Lämpötasapaino
(Turun yliopisto, 2017-11-01)