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Tannins and other polyphenols in Geranium sylvaticum : Identification, intraplant distribution and biological activity
(Turun yliopisto, 2018-01-05)
This thesis studies the phenolic compounds of Geranium sylvaticum L. It focuses especially on geraniin and related ellagitannins. The literature review covers the phytochemistry of Geranium species, the biological activity ...
[18F]F2 – New production methods and applications
(Turun yliopisto, 2018-12-19)
Fluorine-18 is a positron emitting radioisotope. It has a half-life of 109.8 min, a simple decay profile and low positron energy as a result of which properties fluorine-18 is an excellent candidate for use in the production ...
Novel 19F NMR sensors for the characterization of higher-order secondary structures of DNA and RNA
(Turun yliopisto, 2018-06-14)
Both DNA and RNA can fold into a variety of non-canonical structures. Non-canonical structures, such as triplexes and G-quadruplexes, are an active research area due to their biological significance and therapeutic potential. ...
Application of NMR metabolomics profiling on questions arising from molecular biology
(Turun yliopisto, 2018-04-20)
In recent years, there has been an increasing interest in utilizing nuclear magnetic resonance (NMR) spectroscopy metabolomics to understand different biochemical mechanisms of living organisms. Metabolomic profiling can ...
The peptide-break technology : a novel approach for protein post-translational modification assays in drug discovery
(Turun yliopisto, 2019-03-15)
The work presented in this thesis describes the development of a universal platform for the biochemical detection of protein post-translational modifications (PTM) using the quenching resonance energy transfer (QRET) ...
Electrochemical fabrication of nanocomposites towards sustainable energy applications
(Turun yliopisto, 2019-03-08)
In the fight against climate change, effective energy storage applications are required to efficiently store the energy of renewable sources. Supercapacitors are one of the energy storage applications under vigorous research ...
Modifying upconverting nanoparticles with polyelectrolyte multilayers
(Turun yliopisto, 2019-04-12)
Upconversion luminescence where visible light can be obtained through low energy near-infrared radiation is an interesting research topic especially within the scope of biomedical applications using optical detection. The ...
Radiosynthesis of [¹⁸F]F-DPA with various molar activities for the imaging of neuroinflammation
(Turun yliopisto, 2019-06-14)
The use of radioisotopes as a means to non-invasively look into living subjects influenced both diagnostic and therapeutic medicine in the past century. Nowadays positron emission tomography (PET), employing short-lived ...
Synthetic hackmanites and their optical properties – from theory to applications
(Turun yliopisto, 2019-05-17)
Synthetic hackmanite is a material that resembles the natural mineral, hackmanite. The structure of hackmanite, Na8Al6Si6O24(Cl,S)2, together with its simple preparation with solid state synthesis enables the doping of ...
Studies on cationic polythiophenes with hydrogen-bonding donor capabilities
(Turun yliopisto, 2019-11-08)
This project focuses on cationic isothiouronium polythiophenes (CITs), a particular type of conjugated polyelectrolytes (CPEs). In general, CPEs combine a pi-conjugated polymer backbone with pendant ionic groups, which ...