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Acute appendicitis – a study with special reference to diagnostics, severity assessment and association with appendiceal neoplasms
(2019-03-01)
Acute appendicitis is the most common indication for emergency abdominal surgery. Today, it is generally accepted that acute appendicitis does not invariably progress to perforation. Recent studies have shown that the ...
INSIGHT ON THYMOSIN BETA 4 IN ANIMAL MODELS OF MYOCARDIAL INJURY
(Turun yliopisto, 2017-10-27)
The use of small and large animal models is vital in the clinical translation of experimental data in cardiovascular research. Thymosin beta 4 is a peptide which has shown good cardioprotective potential in several in vitro ...
Studies on prostate-specific antigen and prostate cancer epidemiology
(2017-12-15)
The prostate-specific antigen (PSA) is the main biomarker for diagnosis and treatment response monitoring in prostate cancer (PCa). In the first part of this thesis, we investigated the prognostic value of ultrasensitive ...
Clinical and molecular manifestations of lower limb peripheral artery disease
(Turun yliopisto, 2017-11-10)
Lower limb peripheral artery disease (PAD) is poorly known by the general public and even health care professionals. The manifestations of PAD are diverse depending on the prevailing cardiovascular risk factors leading to ...
Outcomes after ascending aortic surgery : registry-based studies with special emphasis on reoperations and pre-operative cardiac arrest
(Turun yliopisto, 2019-08-23)
Surgical repair for ascending aorta regarding an aneurysm or an acute type A aortic dissection (ATAAD) share similar principals in techniques. ATAAD is highly lethal, and the appropriate extent of surgery at acute setting ...
Diagnosis and treatment of obstetric anal sphincter injuries
(Turun yliopisto, 2019-09-13)
Aims: The aims of this study were to identify the risk factors for a failed primary repair of obstetric anal sphincter injury (OASI), to determine whether external phased-array magnetic resonance imaging (MRI) is suitable ...
Neoadjuvant chemotherapy in muscle-invasive bladder cancer
(Turun yliopisto, 2020-08-28)
Bladder cancer can be divided into non-muscle-invasive and muscle-invasive types. In the muscle-invasive type of bladder cancer, removal of the bladder and internal genitalia is the cornerstone of treatment. Treatment ...
The WHO surgical safety checklist in neurosurgery
(Turun yliopisto, 2019-12-13)
The World Health Organization’s surgical safety checklist (WHO SSC) is designed to improve adherence to operating room safety standards. Its use has been shown to reduce surgical morbidity and mortality. Studies on solely ...
Challenges in diagnostics of Prostate cancer
(Turun yliopisto, 2020-05-29)
Prostate cancer (PCa) is the most frequently diagnosed cancer in men and it is one of the leading causes of men’s cancer deaths in the developed countries. It can be considered as a continuum of neoplasms with aggressiveness ...
Congenital abdominal wall defects in Finland 1993-2014 : Epidemiology and risk factors
(Turun yliopisto, 2020-08-21)
Congenital abdominal wall defects are a group of malformations among which gastroschisis and omphalocele are the most common. In omphalocele, abdominal organs are herniated through an open umbilical ring and the defect is ...