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Splanchnic region comprises the interaction of multiple organs, hormones and neural factors and is a critical regulator of glucose homeostasis during both postabsorptive and absorptive states. While ...

Blood pressure (BP) variability is an independent risk factor for cardiovascular adverse events over and beyond the BP level. The clinical significance of BP variability has been extensively studied in the past few decades. ...

Brown adipose tissue (BAT) is a functional and metabolically active tissue found in humans. Instead of storing energy like white adipose tissue (WAT), BAT dissipates energy in the form of heat in a process called thermogenesis. ...

The number of individuals affected by Type 2 diabetes mellitus (T2DM) is increasing rapidly nearly everywhere in the world. Insulin resistance, which means reduced impact of insulin in its target tissues, especially in the ...

The cornerstone of the treatment of early rheumatoid arthritis (RA) is intensive, clinical remission targeted treatment with disease-modifying antirheumatic drugs (DMARDs). The aim of the present study was to elucidate ...

ABSTRACT Patients with peripheral arterial disease (PAD) undergoing surgical revascularisation are in high risk of postoperative cardiovascular complications and death, due to advancing age and multiple comorbidities ...

Thyroid dysfunctions, especially subclinical forms, are common and could be related to an elevated cardiovascular risk. Previous data on the associations of thyroid function with cardiovascular disease entities and their ...

Background: High physical activity and cardiorespiratory fitness may protect from the development of cardiometabolic disease outcomes but the mechanisms involved are not fully understood. Aims: The aims of this study ...

The global epidemic of obesity is a challenge to healthcare systems due to the increase in the incidence of type 2 diabetes (T2D) and its associated morbidities. Although the small intestine is the first absorptive organ ...

Obesity is a significant and increasing health challenge. Obesity is strongly associated with the incidence of type 2 diabetes (T2D). In obese individuals, liver insulin resistance is a major factor in the development and ...