Hae
Aineistot 41-50 / 145
The iron-entry pores in Dps-like proteins as a potential drug-design targe: Structural investigations
(2022-06-01)
Streptococcus suis is an emerging catalase-negative zoonotic pathogen that uses the peroxide resistance protein (Dpr) as a defensive mechanism against oxidative stress. Dpr belongs to a family of proteins that form spherical ...
Unen ja lihavuuden yhteys lapsuudessa
(2022-02-22)
Tämän tutkielman aiheena on unen ja lihavuuden välinen yhteys lapsuudessa. Päätavoitteena on selvittää unen eri komponenttien ja lihavuuden välisiä yhteyksiä lapsuudessa, arvioiden etenkin yhteyksien taustalla vaikuttavia ...
Retinal plasticity in the context of a partially rescued retinitis pigmentosa mouse model
(2022-03-28)
Retinitis pigmentosa (RP) is a major cause of hereditary blindness and visual disability. The prevalence of RP is estimated to be 1/4000, affecting approximately 2.5 million people worldwide. RP is a very slow-progressing ...
Nivus- ja reisityrät
(2022-02-23)
Syventävien opintojen projektityöni koostui kirjallisesta työstä sekä kolmesta muusta osa-alueesta. Kirjallisen työn laadin itsenäisesti ja muut osa-alueet ovat toteutettu yhdessä Maija Lukanderin sekä Wilma Grönroosin ...
BCR signaling and dynamic micropatterns
(2021-12-02)
B lymphocytes (B cells) are an important part of the adaptive immune system. Recognition of surface presented antigen, typically on antigen presenting cell (APC), by the B cell receptor (BCR) triggers BCR signaling cascades ...
Verenpaineen säätelyn ja kohonneen verenpaineen lääkehoidon opiskelu hyödyntäen interaktiivista H5P-verkkotyökalua
(2022-02-03)
Kohonnut verenpaine on merkittävä terveyteen haitallisesti vaikuttava tekijä. Maailmanlaajuisesti se aiheuttaa eniten terveiden elinvuosien menetystä verrattuna muihin terveydellisiin riskitekijöihin. Yli 30-vuotiaista ...
The Process of Digital Pathology and its Application in a Study
(2022-03-23)
Digital pathology saw its advent in the 60’s with the introduction of telepathology and was brought into a brighter spotlight in the late 90’s through the technological breakthrough in histopathological imaging, called ...
TLR9 deficiency promotes bone resorption and induces IL-18 expression upon zoledronate treatment
(2022-03-18)
The aim of this study was to determine the effects of TLR9 deficiency on zoledronate-induced inflammation and bone formation. TLR9 is an intracellular DNA receptor expressed in innate immune system cells. Zoledronate is a ...
Role of Glucose Transporters in osteoblastic cells
(2022-01-31)
Human skeleton is undergoing a constant remodeling through coupled actions of bone resorbing osteoclasts and bone forming osteoblasts and this remodeling process requires a constant source of energy for the cells. Different ...
Discovery of RAR-related Orphan Receptor γt Inverse Agonists
(2021-11-30)
BACKGROUND
Technological advances have provided modern approaches for drug discovery and development. Its application, computer-aided drug design (CADD), enables solving complex drug design challenges practically unsolvable ...