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spa typing of methicillin resistant Staphylococcus aureus in Southwest Finland in 2007 and 2008: Evaluating a method transition and strain type diversity
(2019-03-10)
Staphylococcus aureus is a major cause of both nosocomial and community acquired infections. Methicillin resistant S. aureus (MRSA) strains complicate the effective antimicrobial treatment of these infections. They are a ...
CELL-TYPE SPESIFIC CD73 EXPRESSION IS AN INDEPENDENT PROGNOSTIC FACTOR IN BLADDER CANCER
(2018-11-06)
CD73 is an adenosine-producing cell surface enzyme, which exerts strong anti-inflammatory and migration modulating effects in many cell types. We evaluated the potential of CD73 as a biomarker in predicting the outcome of ...
Nielutulehduksia aiheuttaneiden A-streptokokkien emm-tyypit Varsinais-Suomessa
(2018-10-24)
Streptococcus pyogenes eli A-streptokokki (GAS, Group A Streptococcus) on kokkibakteeri, joka on merkittävä ihmisen taudinaiheuttaja. Sen aiheuttamien infektioiden vakavuusasteet vaihtelevat lievistä nielutulehduksista ...
CD206 in colon cancer
(2020-03-17)
The assessment of immunologic milieu in cancer tissue has proven to be a powerful factor in estimation of disease outcome. The basic idea is to characterize the presence of different immune cell types within tumor tissue. ...
The role of PLVAP protein in endothelial cells of liver
(2021-02-09)
In endothelial cells (EC) PLVAP protein forms permeability regulating structures known as diaphragms. In some previous studies it has been stated that PLVAP does not exist in adult liver ECs, because diaphragms of liver ...
ORIGINS OF ANTIBODY DIVERSITY AND THE ROLE OF BACH2 IN SOMATIC HYPERMUTATION
(2021-03-16)
Antibodies produced by B cells are critical for our immunological defence against pathogens. For antibodies, the ability to recognise and bind pathogenic antigens improves through time during infection. Improvement is due ...
Synnytys- ja lapsivuodeajan infektiot ja niiden mikrobietiologia Varhan alueella vuosina 2013–2022
(2024-03-26)
Lapsivuodeaika tarkoittaa 6–8 synnytyksenjälkeistä viikkoa, jolloin äidin elimistö palaa raskautta edeltäneeseen tilaan. Lapsivuodeajan infektiot ovat merkittävä äidin ja vastasyntyneen sairastavuuden ja kuolleisuuden ...
CD47 and TREM2 for macrophage-targeted cancer immunotherapy: Antibody validation and ex vivo efficacy in patient-derived explant cultures
(2024-03-13)
Cancer remains a common cause of death worldwide. Cancer cells develop several mechanisms to escape immune destruction, which limits the efficacy of current treatments and creates a need for new therapies. Cancer immunotherapies ...