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Aggregatibacter actinomycetemcomitansin tyypin IV piluksen alayksikkö PilA virulenssitekijänä ja sen rakenteelliset ominaisuudet
(2019-09-09)
Aggregatibacter actinomycetemcomitans on patogeeninen gram-negatiivinen suubakteeri, joka osallistuu hampaiden tukikudoksia tuhoavan parodontiitin syntyyn. Patogeenisten bakteerien virulenssiin, eli taudinaiheuttamiskykyyn, ...
Molecular Endophenotypes of Mood and Schizophrenia in Mice
(2020-03-30)
JNK pathway inhibition has been shown to reduce anxiety-like behaviour in rodent models. However, the JNK pathway is also implicated in schizophrenia and precisely how, is still unknown. To gain basic understanding on how ...
Myxovirusresistenssi-proteiini A pikatestin kehitys ja optimointi
(2019-03-14)
Antibioottiresistenssi on globaali uhka. Mikrobilääkeresistenssi aiheuttaa vuosittain 750 000 ihmisen kuoleman. Antibioottiresistenssi lisää huomattavasti terveydenhuollon kustannuksia, pidentää hoitojaksoja ja huonontaa ...
Comparison of effects of different methods for deodorizing sturgeon fish (Acipenser sinensis)
(2019-06-26)
In recent years, sturgeon fish (Acipenser sinensis) has become a popular freshwater-farmed fish in China with high nutritional and economic value. However, the utility of the fish flesh is quite low – the unwanted fishy ...
Differential detection of cancer antigen-125 glycovariant for the diagnosis of epithelial ovarian cancer
(2020-04-01)
Cancer antigen 125 (CA125) is the established serum biomarker for epithelial ovarian cancer (EOC) diagnostic, however, it is also elevated in benign conditions such as endometriosis. Altered glycosylation during cancer ...
Effects of vitamin B3 supplementation on NAD+ biosynthesis and mitochondrial metabolism in human muscle and white adipose tissue
(2020-05-22)
The complex pathophysiology of obesity-related disturbances is closely linked to mitochondria malfunction. Therefore, boosting mitochondrial activity could protect from metabolic complications. Based on animal studies, an ...