Julkaisuarkisto

The accelerating ‘green transition’ in northern Sweden and Finland has intensified competition over land and natural resources, particularly in areas traditionally used for Sámi reindeer herding. Large-scale mineral extraction and renewable energy projects, reinforced by recent EU initiatives such as the Critical Raw Materials Act (CRMA) and the revised Renewable Energy Directive (RED III), place increasing pressure on national planning systems to deliver rapid yet sustainable decisions. This raises fundamental questions about the capacity of strategic spatial planning to manage cumulative effects, prioritise competing land-uses, and safeguard Indigenous rights. This article undertakes a legal-comparative analysis of strategic spatial planning instruments in Sweden and Finland. It examines, trends, the function and legal effects of regional plans, the role of the state and the responsible authority for regional planning, and the interaction with mining law and EU requirements. The analysis demonstrates that Sweden and Finland currently pursue fundamentally different approaches to strategic spatial planning. Finland retains a more integrated and legally structured planning hierarchy, where regional plans have a coordinating role in relation to mining and competing land uses, including Sámi reindeer herding. Sweden, by contrast, relies more heavily on sectoral legislation and permitting procedures. The article further shows that cumulative land-use pressures and landscape-scale conflicts are difficult to manage through municipal planning alone. It argues that recent EU legislation increases the need for stronger strategic and supra-municipal planning frameworks capable of coordinating competing land uses and integrating Indigenous rights and cumulative impact assessments into long-term land-use governance.

Hackmanites are a class of materials that exhibit diverse and intriguing optical characteristics, including luminescence andtenebrescence. Doping with other luminescent species would unveil a fresh spectrum of optical properties and potentialapplications. This project aimed to successfully dope a lithium derivative of hackmanite with highly luminescent lanthanides (Sm³⁺, Eu³⁺, Tb³⁺, and Dy³⁺) using a doped aluminosilicate precursor, LiAlSiO₄. Initial structural analysis indicated successfuldoping with little disruption to the host lattice. Luminescence spectroscopy revealed that the emissive properties of the lanthanideions were largely suppressed upon incorporation into the sodalite due to the presence of other highly luminescent impurities.However, europium-doped samples exhibited emission from both Eu²⁺ and Eu³⁺, with the former resulting in long-lasting greenpersistent luminescence. Room-temperature persistent luminescence was determined to arise from traps at a depth of 0.3 eV. Incontrast, doping with samarium yielded a photochromic response atypical of traditional hackmanites, characterized by absorptionextending into the near-infrared region. Spectroscopic evidence suggested the involvement of Sm²⁺/Sm³⁺ redox processes coupledto disulphide photochromic centers in the tenebrescence mechanism. Lanthanide doping provides a versatile route for modifyingboth the luminescence and photochromic behavior of hackmanites, enabling additional functionalities in lighting applicationsand UV dosimetry.

Importance  Anticoagulation for stroke prevention in subclinical, device-detected atrial fibrillation (AF) remains an area of clinical equipoise, and its cost-effectiveness is unknown.

Objective  To evaluate the cost-effectiveness of direct oral anticoagulant (DOAC) therapy in patients with device-detected AF.

Design, Setting, and Participants  This economic evaluation was a cost-effectiveness analysis using a Markov model comparing initiation of DOAC therapy vs no anticoagulation over a 10-year time horizon. Base-case analyses modeled 10 000 patients per strategy with device-detected subclinical AF, with baseline characteristics and risks of stroke, bleeding, and mortality reflecting those observed in randomized clinical trials. The evaluation was conducted from the health system perspective, with treatment and event costs derived from Nordic health care data. The modeling was conducted on March 10, 2026.

Exposure  The associations of DOAC therapy with the risk and severity of clinical events were incorporated into the analysis, based on a meta-analysis of trials evaluating DOAC therapy in subclinical AF. Probabilistic sensitivity analysis also considered the 95% CIs in the reported treatment effect sizes.

Main Outcomes and Measures  Incremental quality-adjusted life-years (QALYs), costs, and the incremental cost-effectiveness ratio (ICER; cost difference per QALY gained) from a health system perspective, with 3% annual discounting of both costs and QALYs. Cost-effectiveness was assessed using a €50 000 per QALY willingness-to-pay threshold.

Results  The mean age of the 20 000-person simulated cohort was 77 years. In the base case analysis, DOAC therapy was associated with an additional 0.016 QALYs and an incremental cost of €1676 per patient, resulting in an ICER of €105 293 per QALY. In probabilistic sensitivity analysis, DOAC therapy was cost-effective in 35% of simulations and dominated in 38%, with a mean QALY gain of 0.016 per patient, a mean incremental cost of €2883 per patient, and a mean ICER of €176 772. Probabilistic sensitivity analyses by CHA₂DS₂-VASc (congestive heart failure; hypertension; age ≥75 years; diabetes; prior stroke, transient ischemic attack, or thromboembolism; vascular disease; age 65-74 years; and sex category) score showed probabilities of cost-effectiveness of 31%, 41%, and 52% for patients with scores less than 4, of 4, and greater than 4, respectively.

Conclusions and Relevance  This economic evaluation found that routinely initiating DOAC therapy in all patients with device-detected subclinical AF is unlikely to be cost-effective. Whether treatment is cost-effective in patients with very high CHA₂DS₂-VASc scores is uncertain.

As entrepreneurship education (EE) faces mounting pressure to respond to the socio-ecological polycrisis of the Anthropocene, prevailing human-centred, business growth-oriented pedagogies appear increasingly insufficient. This conceptual manuscript advances a critical posthuman practice approach to entrepreneurship education that foregrounds multispecies relationality, response-ability, and ethical co-becoming. Building on entrepreneurship-as-practice scholarship, and drawing in particular on a critical posthumanist practice approach, we extend emerging calls to rethink entrepreneurship (and EE) beyond anthropocentrism by translating multispecies thinking into educational practice. Drawing on illustrative examples from posthuman and eco-relational pedagogies in higher education we develop a set of propositions for a multispecies entrepreneurship pedagogy to reimagine EE as embodied, situated, and relational, involving both human and more-than-human actors as co-participants.

We argue that such a pedagogy can cultivate response-able entrepreneurs oriented toward ecological justice, care, and multispecies flourishing. The manuscript contributes to entrepreneurship-education-as-practice by offering a novel theoretical framing and concrete pedagogical orientations for post-anthropocentric futures.