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Biomarkers of kidney function and prediction of death from cardiovascular and other causes in the elderly: A 9-year follow-up study
Background: Cystatin C is claimed to be superior to creatinine-based estimates of glomerular filtration rate (eGFRcr). The purpose of the study is to analyze whether cystatin C, creatinine, and/or estimated glomerular ...
Insights into disseminated MS brain pathology with multimodal diffusion tensor and PET imaging
<div>Objective To evaluate in vivo the co-occurrence of microglial activation and microstructural white matter (WM) damage in the MS brain and to examine their association with clinical disability.</div><div>Methods 18-kDa ...
Deep neck space infections: an upward trend and changing characteristics
<p>Purpose This study reviews our experience with deep neck space infections (DNIs) requiring surgical intervention, includingcervical necrotizing fasciitis. The aim of the study was to identify predisposing and aggravating ...
Immunological Reconstitution in Children After Completing Conventional Chemotherapy of Acute Lymphoblastic Leukemia is Marked by Impaired B-cell Compartment
Humoral and cellular immunity were studied in 28 children completing conventional treatment of standard-risk (SR) or intermediate-risk (IR) acute lymphoblastic leukemia (ALL). Both naive and memory B cells were most severely ...
Lentomatkaa suunnittelevan keuhkopotilaan arviointi
Lentokoneen matkustamossa vallitsevat poikkeavat paineolosuhteet ja merenpinnan tasoa matalampi happiosapaine. Keuhkopotilailla on erityinen vaara saada oireita lennon aikana.Lentomatkaa suunnitellessa tulee ottaa huomioon ...
Healthy full-term infants’ brain responses to emotionally and linguistically relevant sounds using a multi-feature mismatch negativity (MMN) paradigm
<p>We evaluated the feasibility of a multi-feature mismatch negativity (MMN) paradigm in studying auditory processing of healthy newborns. The aim was to examine the automatic change-detection and processing of semantic ...
Rapid detection of bacterial infection using a novel single-tube, four-colour flow cytometric method: Comparison with PCT and CRP
<p>Background<br></p><p>A key factor behind the unnecessary use of antibiotics is the lack of rapid and accurate diagnostic tests. In this study, we developed a novel and fast flow cytometric single-tube method to detect ...
Computational Analysis of HLA-presentation of Non-synonymous Recipient Mismatches Indicates Effect on the Risk of Chronic Graft-vs.-Host Disease After Allogeneic HSCT
Genetic mismatches in protein coding genes between allogeneic hematopoietic stem cell transplantation (allo-HSCT) recipient and donor can elicit an alloimmunity response via peptides presented by the recipient HLA receptors ...
Brown fat triglyceride content is associated with cardiovascular risk markers in adults from a tropical region
Brown adipose tissue (BAT) is regarded as an interesting potential target for the treatment of obesity, diabetes, and cardiovascular diseases, and the detailed characterization of its structural and functional phenotype ...