Viimeksi syötetyt 3. UTUCris-artikkelit
Aineistot 13101-13120 / 27094
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Structure of Collagen Receptor Integrin alpha I-1 Domain Carrying the Activating Mutation E317A
We have analyzed the structure and function of the integrin alpha I-1 domain harboring a gain-of-function mutation E317A. To promote protein crystallization, a double variant with an additional C139S mutation was used. In ... -
How Do Adolescents Use Electronic Diaries? A Mixed-Methods Study Among Adolescents With Depressive Symptoms
Background: Depression in adolescence is common. Less than half of the adolescents with depression receive mental health care; furthermore, treatment tends to be suspended, and its success rates are low. There is a need ... -
Nimetön
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A cost-effective method for producing spatially continuous high-resolution air temperature information in urban environments
<p><br></p><p>Sustainable city planning requires detailed information on spatial temperature variations. Remotely sensed land surface temperature (LST) is known to differ substantially from air temperature (AT) causing ... -
An educational intervention for NICU staff decreased maternal postpartum depression
<h3>Background</h3><p>Mothers of preterm infants are at increased risk for postpartum depression, which may disturb parenting and child development. Strategies for prevention are needed. Therefore, we evaluated how an ... -
UBR5 Is Coamplified with MYC in Breast Tumors and Encodes an Ubiquitin Ligase That Limits MYC-Dependent Apoptosis
For maximal oncogenic activity, cellular MYC protein levels need to be tightly controlled so that they do not induce apoptosis. Here, we show how ubiquitin ligase UBR5 functions as a molecular rheostat to prevent excess ... -
Rediscovery of Geophilus carpophagus Leach (Chilopoda: Geophilomorpha) from Finland
<p><i>Geophilus carpophagus</i> Leach, 1815 has long been listed as regionally extinct from Finland. Here we report its rediscovery after decades of absence.</p> -
Temporal development of the gut microbiome in early childhood from the TEDDY study
The development of the microbiome from infancy to childhood is dependent on a range of factors, with microbial-immune crosstalk during this time thought to be involved in the pathobiology of later life diseases(1-9) such ... -
Increased Health and Wellbeing in Preschools DAGIS) Study—Differences in Children’s Energy Balance-Related Behaviors (EBRBs) and in Long-Term Stress by Parental Educational Level
<p>This paper describes the Increased Health and Wellbeing in Preschools (DAGIS) survey process and socioeconomic status (SES) differences in children’s energy balance-related behaviors (EBRBs), meaning physical activity, ... -
Oxidation of an Oligonucleotide-Bound Ce-III/Multiphosphonate Complex for Site-Selective DNA Scission
Oligodeoxyribonucleotide conjugates of ethylenediamine-N,N,N',N'-tetrakis(methylenephosphonic acid) (EDTP) have been used to place a Ce-III/EDTP complex in close proximity to predetermined phosphodiester linkages of a ... -
Nimetön
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Children's physical activity and active travel: a cross-sectional study of activity spaces, sociodemographic and neighborhood associations
Measures of individual mobility, such as activity space, have been previously used to help improve our understanding of individuals' interactions with their everyday environments. However, such methods have rarely been ... -
Kun itänaapuri vaihtui - Suomi, Neuvostoliiton hajoaminen ja Venäjän nousu 1990–1992
<p>Neuvostoliiton hajoaminen on 1900-luvun keskeisimpiä poliittisia tapahtumia. Yksi ratkaisevimmin prosessiin vaikuttaneista tekijöistä oli kansallisuuskysymys – erityisesti Venäjän itsenäisyyspyrkimykset. Neuvostoliiton ... -
Nimetön
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Loss of ADAM9 expression impairs beta 1 integrin endocytosis, focal adhesion formation and cancer cell migration
The transmembrane protease ADAM9 is frequently upregulated in human cancers, and it promotes tumour progression in mice. In vitro, ADAM9 regulates cancer cell adhesion and migration by interacting with integrins. However, ... -
Family life courses, gender, and mid-life earnings
<p>There is a long-standing debate on whether extensive Nordic family policies have the intended equalizing effect on family and gender differences in economic outcomes. This article compares how the combination of family ...