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Association between arterial hypertension and liver outcomes using polygenic risk scores: a population-based study
<p>Arterial hypertension (HTA) is associated with liver disease, but causality remains unclear. We investigated whether genetic predisposition to HTA is associated with liver disease in the population, and if antihypertensive ... -
Early prediction of incident liver disease using conventional risk factors and gut-microbiome-augmented gradient boosting
The gut microbiome has shown promise as a predictive biomarker for various diseases. However, the potential of gut microbiota for prospective risk prediction of liver disease has not been assessed. Here, we utilized shallow ... -
Links between gut microbiome composition and fatty liver disease in a large population sample
Fatty liver disease is the most common liver disease in the world. Its connection with the gut microbiome has been known for at least 80 y, but this association remains mostly unstudied in the general population because ... -
Persistent oral mucosal lesions preceding diagnosis of Crohn's disease and primary sclerosing cholangitis
Oral mucosal lesions may persist years before symptoms or diagnosis of inflammatory bowel disease (IBD) and subsequent primary sclerosing cholangitis (PSC). Since a dental practitioner may be the first clinician to suspect ...
