Hae
Aineistot 31-40 / 55
Effects of 6 weeks of treatment with dapagliflozin, a sodium- glucose co-transporter-2 inhibitor, on myocardial function and metabolism in patients with type 2 diabetes: A randomized, placebo-controlled, exploratory study
<p><strong>Aim: </strong>To explore the early effects of dapagliflozin on myocardial function and metabolism in patients with type 2 diabetes without heart failure.</p><p><strong>Materials and methods: </strong>Patients ...
Aerobic Fitness is Associated with Cerebral mu-Opioid Receptor Activation in Healthy Humans
<p><strong>Introduction: </strong>Central μ-opioid receptors (MORs) modulate affective responses to physical exercise. Individuals with higher aerobic fitness report greater exercise-induced mood improvements than those ...
Association of CNR1 gene and cannabinoid 1 receptor protein in the human brain
We aimed to integrate genomic mapping from brain mRNA atlas with the protein expression from positron emission tomography (PET) scans of type 1 cannabinoid (CB1) receptor and to compare the predictive power of CB1 receptor ...
Obesity risk is associated with brain glucose uptake and insulin resistance
<p><strong>Objective: </strong>To investigate whether alterations in brain glucose uptake (BGU), insulin action in the brain-liver axis and whole-body insulin sensitivity occur in young adults in pre-obese state.</p><p>< ...
Comparison of the prognostic value of early-phase proton magnetic resonance spectroscopy and diffusion tensor imaging with serum neuron-specific enolase at 72 h in comatose survivors of out-of-hospital cardiac arrest-a substudy of the XeHypotheca trial
<p><strong>Purpose: </strong>We compared the predictive accuracy of early-phase brain diffusion tensor imaging (DTI), proton magnetic resonance spectroscopy (1H-MRS), and serum neuron-specific enolase (NSE) against the ...
miR-125b affects mitochondrial biogenesis and impairs brite adipocyte formation and function
Objective: In rodents and humans, besides brown adipose tissue (BAT), islands of thermogenic adipocytes, termed "brite" (brown-in-white) or beige adipocytes, emerge within white adipose tissue (WAT) after cold exposure or ...
Myocardial perfusion reserve of kidney transplant patients is well preserved
<p><strong>Background</strong>: Chronic kidney disease (CKD) is associated with endothelial dysfunction and increased cardiovascular mortality. Endothelial dysfunction can be studied measuring myocardial perfusion reserve ...
Glucagon-like peptide-1 receptor expression after myocardial infarction: Imaging study using [68Ga]NODAGA-exendin-4 positron emission tomography
<h3>BACKGROUND: </h3><div><p>Activation of glucagon-like peptide-1 receptor (GLP-1R) signaling protects against cardiac dysfunction and remodeling after myocardial infarction (MI). The aim of the study was to evaluate ...
Pancreatic metabolism, blood flow, and β-cell function in obese humans.
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<span class="hlFld-FullText">Glucolipotoxicity is believed to induce pancreatic β-cell dysfunction in obesity. Previously, it ...