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Clinical correlates of rhinovirus infection in preschool asthma
Background Investigation of preschool asthma is important since not all children outgrow their illness during this age. Data are scarce on the role of rhinovirus (RV) infections in this patient group. Objectives To investigate ...
Mechanism of Rhinovirus Immunity and Asthma
The majority of asthma exacerbations in children are caused by Rhinovirus (RV), a positive sense single stranded RNA virus of the Picornavirus family. The host has developed virus defense mechanisms that are mediated by ...
Regulated on Activation, Normal T cell Expressed and Secreted (RANTES) drives the resolution of allergic asthma
RANTES is implicated in allergic asthma and in T cell-dependent clearance of infection. RANTES receptor family comprises CCR1, CCR3, and CCR5, which are G-protein-coupled receptors consisting of seven transmembrane helices. ...