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Reproductive Markers of Testicular Function and Size During Puberty in Boys With and Without a History of Cryptorchidism
<p><b>Context</b><br></p><p>Longitudinal data on levels of hypothalamic-pituitary-gonadal axis hormones and insulin-like growth factor I (IGF-I) during puberty in boys with a history of cryptorchidism are largely ...
Medical and midwifery students need increased sexual medicine education to overcome barriers hindering bringing up sexual health issues - A national study of final-year medical and midwifery students in Finland
<p><strong>Objectives: </strong>Physicians and midwives meet patients with sexual health issues regularly; however, they may have limited sexual medicine education. The study's aim was to evaluate the self-reported competence ...
Let's talk about sexuality - A web-based survey of self-reported competence in sexual problems among obstetrician-gynecologists in Finland
<p><strong>Introduction: </strong>Sexual health is an important aspect of quality of life, yet both healthcare professionals and patients might hesitate to bring up the topic during appointments. Our study investigated ...
Potential pathobionts in vaginal microbiota are affected by fish oil and/or probiotics intervention in overweight and obese pregnant women
<div><p>New means to stabilize the microbial balance during pregnancy could benefit maternal health. Our objectives were to investigate in overweight/obese pregnant women 1) the impact of long-chain <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/polyunsaturated-fatty-acid" title="Learn more about polyunsaturated fatty acids from ScienceDirect's AI-generated Topic Pages">polyunsaturated fatty acids</a> (fish oil) and/or <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/probiotic-agent" title="Learn more about probiotics from ScienceDirect's AI-generated Topic Pages">probiotics</a> on the <a href="https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/vagina-flora" title="Learn more about vaginal microbiota from ScienceDirect's AI-generated Topic Pages">vaginal microbiota</a>, 2) its relation to <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/gestational-diabetes" title="Learn more about gestational diabetes mellitus from ScienceDirect's AI-generated Topic Pages">gestational diabetes mellitus</a> (GDM) and 3) its interaction with vaginal active matrix metalloproteinase-8 (aMMP-8) and serum high sensitivity C-reactive protein (hsCRP) and phosphorylated insulin-like growth factor-binding protein-1 (phIGFBP-1), IGFBP-1 and aMMP-8.<br></p><p>The women were allocated to fish oil + placebo, probiotics + placebo, fish oil + probiotics and placebo + placebo-groups, from <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/first-trimester-pregnancy" title="Learn more about early pregnancy from ScienceDirect's AI-generated Topic Pages">early pregnancy</a> onwards (fish oil: 1.9 g <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/docosahexaenoic-acid" title="Learn more about docosahexaenoic acid from ScienceDirect's AI-generated Topic Pages">docosahexaenoic acid</a> and 0.22 g <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/icosapentaenoic-acid" title="Learn more about eicosapentaenoic acid from ScienceDirect's AI-generated Topic Pages">eicosapentaenoic acid</a>; probiotics: Lacticaseibacillus rhamnosus HN001 (formerly <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/lactobacillus" title="Learn more about Lactobacillus from ScienceDirect's AI-generated Topic Pages">Lactobacillus</a> rhamnosus HN001) and <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/bifidobacterium-animalis" title="Learn more about Bifidobacterium animalis from ScienceDirect's AI-generated Topic Pages">Bifidobacterium animalis</a> ssp. lactis 420, 10<sup>10</sup> colony-forming units each). Vaginal and serum samples (early pregnancy, n = 112; <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/third-trimester-pregnancy" title="Learn more about late pregnancy from ScienceDirect's AI-generated Topic Pages">late pregnancy</a>, n = 116), were analyzed for vaginal microbiota using <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/rna-16s" title="Learn more about 16S rRNA from ScienceDirect's AI-generated Topic Pages">16S rRNA</a> gene <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/amplicon" title="Learn more about amplicon from ScienceDirect's AI-generated Topic Pages">amplicon</a> sequencing and vaginal aMMP-8 and serum hsCRP, aMMP-8, phIGFBP-1 and IGFBP-1 by <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/immunoassay" title="Learn more about immunoassays from ScienceDirect's AI-generated Topic Pages">immunoassays</a>. GDM was diagnosed from a 2-h 75 g <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/oral-glucose-tolerance-test" title="Learn more about OGTT from ScienceDirect's AI-generated Topic Pages">OGTT</a>. ClinicalTrials.gov, NCT01922791.</p><p>The intervention exerted effects on many low-abundant bacteria. Compared to the placebo-group, there was a lower abundance of potential pathobionts, namely <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/ureaplasma" title="Learn more about Ureaplasma from ScienceDirect's AI-generated Topic Pages">Ureaplasma</a> urealyticum in the fish oil-group, Ureaplasma, U. urealyticum and <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/prevotella" title="Learn more about Prevotella from ScienceDirect's AI-generated Topic Pages">Prevotella</a> disiens in the probiotics-group, <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/dialister" title="Learn more about Dialister from ScienceDirect's AI-generated Topic Pages">Dialister</a> invisus and Prevotella timonensis in the fish oil + probiotics-group. Moreover, probiotics decreased the abundance of a few potential pathobionts during pregnancy. Many bacteria were related to GDM. The vaginal aMMP-8 level correlated significantly with α-diversity and inversely with two Lactobacillus species.</p><p>Dietary interventions, especially probiotics, may have beneficial effects on the vaginal microbiota during pregnancy.</p></div>...
The efficacy of probiotics and/or n-3 long-chain polyunsaturated fatty acids intervention on maternal prenatal and postnatal depressive and anxiety symptoms among overweight and obese women
Maternal depression and anxiety may endanger well-being of both mother and child. We investigated the efficacy of probiotics and/or fish oil (FO) in modifying pre- and postnatal depressive and anxiety symptoms. Symptom ...