Hae
Aineistot 1-4 / 4
Frailty and mortality: an 18-year follow-up study among Finnish community-dwelling older people
<div><h3>Background</h3><p>There is a lack of agreement about applicable instrument to screen frailty in clinical settings.</p></div><div><h3>Aims</h3><p>To analyze the association between frailty and mortality in Finnish community-dwelling older people.</p></div><div><h3>Methods</h3><p>This was a prospective study with 10- and 18-year follow-ups. Frailty was assessed using FRAIL scale (FS) (n = 1152), Rockwood’s frailty index (FI) (n = 1126), and PRISMA-7 (n = 1124). To analyze the association between frailty and mortality, Cox regression model was used.</p></div><div><h3>Results</h3><p>Prevalence of frailty varied from 2 to 24% based on the index used. In unadjusted models, frailty was associated with higher mortality according to FS (hazard ratio 7.96 [95% confidence interval 5.10–12.41] in 10-year follow-up, and 6.32 [4.17–9.57] in 18-year follow-up) and FI (5.97 [4.13–8.64], and 3.95 [3.16–4.94], respectively) in both follow-ups. Also being pre-frail was associated with higher mortality according to both indexes in both follow-ups (FS 2.19 [1.78–2.69], and 1.69 [1.46–1.96]; FI 1.81[1.25–2.62], and 1.31 [1.07–1.61], respectively). Associations persisted even after adjustments. Also according to PRISMA-7, a binary index (robust or frail), frailty was associated with higher mortality in 10- (4.41 [3.55–5.34]) and 18-year follow-ups (3.78 [3.19–4.49]).</p></div><div><h3>Discussion</h3><p>Frailty was associated with higher mortality risk according to all three frailty screening instrument used. Simple and fast frailty indexes, FS and PRISMA-7, seemed to be comparable with a multidimensional time-consuming FI in predicting mortality among community-dwelling Finnish older people.</p></div><div><h3>Conclusions</h3><p>FS and PRISMA-7 are applicable frailty screening instruments in clinical setting among community-dwelling Finnish older people.</p></div>...
Quality of information transferred to palliative care
<p><strong>Aims and objectives: </strong>To describe the quality of information coming from previous care units to palliative care.</p><p><strong>Background: </strong>Information quality is an interconnected concept that ...
Accessibility of care plan information from previous treatment setting in palliative care unit: A qualitative study
<p><strong>Aim: </strong>To describe accessibility of care plan information from patients' previous treatment setting in palliative care.</p><p><strong>Design: </strong>A qualitative descriptive study.</p><p><strong>Meth ...
Midlife insulin resistance, APOE genotype, and late-life brain amyloid accumulation
ObjectiveTo examine whether midlife insulin resistance is an independent risk factor for brain amyloid accumulation in vivo after 15 years, and whether this risk is modulated by APOE epsilon 4 genotype.MethodsThis observational ...