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Renal hemodynamics and fatty acid uptake: effects of obesity and weight loss
Human studies of renal hemodynamics and metabolism in obesity are insufficient. We hypothesized that renal perfusion and renal free fatty acid (FFA) uptake are higher in subjects with morbid obesity compared with lean ...
MR signal-fat-fraction analysis and T2*weighted imaging measure BAT reliably on humans without cold exposure
Objective. Brown adipose tissue (BAT) is compositionally distinct from white adipose tissue (WAT) in terms of triglyceride and water content. In adult humans, the most significant BAT depot is localized in the supraclavicular ...
Basal and cold-induced fatty acid uptake of human brown adipose tissue is impaired in obesity
<p>atty acids (FA) are important substrates for brown adipose tissue (BAT)
metabolism, however, it remains unclear whether there exists a
difference in FA metabolism of BAT between lean and obese healthy
humans. In ...
Measurement of brown adipose tissue mass using a novel dual-echo magnetic resonance imaging approach: A validation study
Objective<br />The aim of this study was to evaluate and validate magnetic resonance imaging (MRI) for the visualization and quantification of brown adipose tissue (BAT) in vivo in a rat model. We hypothesized that, based ...
miR-125b affects mitochondrial biogenesis and impairs brite adipocyte formation and function
Objective: In rodents and humans, besides brown adipose tissue (BAT), islands of thermogenic adipocytes, termed "brite" (brown-in-white) or beige adipocytes, emerge within white adipose tissue (WAT) after cold exposure or ...