Hae
Aineistot 21-28 / 28
FUNGI: Fusion Gene Integration Toolset
<p><strong>Motivation: </strong>Fusion genes are both useful cancer biomarkers and important drug targets. Finding relevant fusion genes is challenging due to genomic instability resulting in a high number of passenger ...
Prospective Longitudinal ctDNA Workflow Reveals Clinically Actionable Alterations in Ovarian Cancer
PURPOSE Circulating tumor DNA (ctDNA) detection is a minimally invasive technique that offers dynamic molecular snapshots of genomic alterations in cancer. Although ctDNA markers can be used for early detection of cancers ...
Vulvar malignant pleomorphic adenoma in a patient with lichen sclerosus
<p>Lichen sclerosus (LS) is a chronic inflammatory skin disease presenting mainly on the anogenital area. The relationship between female genital LS and squamous cell carcinoma (SCC) has been established, with a lifetime ...
Comprehensive feature selection for classifying the treatment outcome of high-intensity ultrasound therapy in uterine fibroids
The study aim was to utilise multiple feature selection methods in order to select the most important parameters from clinical patient data for high-intensity focused ultrasound (HIFU) treatment outcome classification in ...
Amino acid profile in women with gestational diabetes mellitus treated with metformin or insulin
<p>Aims: We compared the effects of metformin and insulin treatments of gestational diabetes mellitus (GDM) on amino acid metabolism.<br /><br />Methods: 217 pregnant women diagnosed with GDM were randomized to receive ...
Prenatal Glucocorticoid-Exposed Infants Do Not Show an Age-Typical Fear Bias at 8 Months of Age – Preliminary Findings From the FinnBrain Birth Cohort Study
<p>Synthetic glucocorticoids (sGC) are frequently administered to pregnant women at risk for preterm delivery to promote fetal lung maturation. Despite their undeniable beneficial effects in lung maturation, the impact of ...
Placental DNA methylation marks are associated with maternal depressive symptoms during early pregnancy
<p>Maternal depressive symptoms during pregnancy are a significant risk factor for adverse developmental and health outcomes of the offspring. The molecular mechanisms mediating the long-term effects of this exposure are ...