Hae

<p><br></p><p>Osteopontin (OPN), encoded by SPP1, is a phosphorylated glycoprotein predominantly synthesized in kidney tissue. Increased OPN mRNA and protein expression correlates with proteinuria, reduced creatinine ...

<p>Background</p><p>Non-coding RNA 886 (nc886) is coded from a maternally inherited metastable epiallele. We set out to investigate the determinants and dynamics of the methylation pattern at the nc886 epiallele and how ...

<div><p><strong>Background: </strong>Low socio-economic position (SEP) is a risk factor for multiple health outcomes, but its molecular imprints in the body remain unclear.</p><p><strong>Methods: </strong>We examined SEP ...

<div><p><strong>Background: </strong> Women with a history of complications of pregnancy, including hypertensive disorders, gestational diabetes or an infant fetal growth restriction or preterm birth, are at higher risk ...

<p>Objective <br></p><p>This study aimed to investigate the role of cytokines as intermediates in the pathway from increased adiposity to disease.<br></p><p>Methods <br></p><p>BMI and circulating levels of up to 41 cytokines ...

This study quantifies the causal effect of birth weight on cardiovascular biomarkers in adulthood using the Cardiovascular Risk in Young Finns Study (YFS). We apply a multivariable Mendelian randomization (MVMR) method ...

<p><strong>Background: </strong>The links between fatty acids (FAs) and cardiometabolic outcomes are topics of debate.</p><p><strong>Objective: </strong>Our aim was to investigate the associations between serum standardized ...

<p>Chronic kidney disease is a major public health burden. Elevated urinary albumin-to-creatinine ratio is a measure of kidney damage, and used to diagnose and stage chronic kidney disease. To extend the knowledge on ...

<p>INTRODUCTION</p><p>The role of risk factor profile in childhood and adolescence on adulthood cognitive function and whether it differs by genetic risk is still obscure. To bring this evidence, we determined cognitive ...

<p><strong>Objective: </strong>To evaluate the association between childhood parental smoking exposure and the risk of overweight/obesity from childhood to adulthood.</p><p><strong>Methods: </strong>This study leverages ...