Hae
Aineistot 451-460 / 504
Reward and emotion: an affective neuroscience approach
<p>Pleasure and reward are central for motivation, learning, feeling and allostasis. Although reward is without any doubt an affective phenomenon, there is no consensus concerning its relationship with emotion. In this mini-review we discuss this conceptual issue both from the perspective of theories of reward and emotion as well as human systems neuroimaging. We first describe how the reward process can be understood and dissected as intertwined with the emotion process, in particular in light of the appraisal theories, and then discuss how different facets of the reward process can be studied using neuroimaging and <a title="Learn more about neurostimulation from ScienceDirect's AI-generated Topic Pages" href="https://www.sciencedirect.com/topics/neuroscience/neurostimulation"><u>neurostimulation</u></a> techniques. We conclude that future work needs to focus on mapping the similarities and differences across stimuli and mechanisms that are involved in reward processing and in emotional processing, and propose that an integrative affective sciences approach would provide means for studying the emotional nature of reward.<br></p>...
68Ga-NODAGA-exendin-4 PET improves the detection of focal congenital hyperinsulinism
Surgery with curative intent can be offered to Congenital Hyperinsulinism (CHI) patients, provided that the lesion is focal. Radiolabeled Exendin-4 specifically binds the glucagon-like peptide 1 receptor (GLP-1R) on ...
Machine Learning in the Evaluation of Myocardial Ischemia Through Nuclear Cardiology
<div>Purpose of Review</div><div>To summarize the advances achieved in the detection and characterization of myocardial ischemia and prediction of related outcomes through machine learning (ML)-based artificial intelligence ...
Post-target produced [18F]F2 in the production of PET radiopharmaceuticals.
<p>Electrophilic radiofluorination was successfully carried out in the early years of PET radiochemistry due to its ease and fast reaction speed. However, at the present, the use of electrophilic methods is limited due to ...
Blocking activin receptor ligands is not sufficient to rescue cancer-associated gut microbiota - a role for gut microbial flagellin in colorectal cancer and cachexia?
<p>Colorectal cancer (CRC) and cachexia are associated with the gut
microbiota and microbial surface molecules. We characterized the
CRC-associated microbiota and investigated whether cachexia affects the
microbiota ...
Riittääkö tehotreeni?
<p>Kovatehoinen intervalliharjoittelu vaatii työtä kovalla sykkeellä eikä ole oikotie onneen<br /></p>
Ventral striatal dopaminergic defect is associated with hallucinations in Parkinson's disease
<h3>Conclusions</h3><p>Low striatal DAT function may predispose PD patients to VHs, and the regional distribution of the findings suggests a particular role of the ventral striatum. This is in line with non-PD research ...
Increased insulin-stimulated glucose uptake in both leg and arm muscles after sprint interval and moderate intensity training in subjects with Type 2 Diabetes or Prediabetes
<p>We investigated the effects of sprint interval (SIT) and moderate intensity continuous training (MICT) on glucose uptake (GU) during hyperinsulinemic euglycemic clamp and fatty acid uptake (FAU) at fasting state in thigh ...
Head-to-Head Comparison of 68Ga-Citrate and 18F-FDG PET/CT for Detection of Infectious Foci in Patients with Staphylococcus aureus Bacteraemia
<p>Purpose. This study evaluated the potential of <sup>68</sup>Ga-citrate positron emission tomography/computed tomography (PET/CT) for the detection of infectious foci in patients with Staphylococcus aureus bacteraemia by comparing it with 2-[<sup>18</sup>F]fluoro-2-deoxy--glucose (<sup>18</sup>F-FDG) PET/CT. Methods. Four patients admitted to hospital due to S. aureus bacteraemia underwent both <sup>18</sup>F-FDG and <sup>68</sup>Ga-citrate whole-body PET/CT scans to detect infectious foci. Results. The time from hospital admission and the initiation of antibiotic treatment to the first PET/CT was 4–10 days. The time interval between <sup>18</sup>F-FDG and <sup>68</sup>Ga-citrate PET/CT was 1–4 days. Three patients had vertebral osteomyelitis (spondylodiscitis) and one had osteomyelitis in the toe; these were detected by both <sup>18</sup>F-FDG (maximum standardised uptake value [SUV<sub>max</sub> 6.0 ± 1.0] ) and <sup>68</sup>Ga-citrate (SUV<sub>max</sub> 6.8 ± 3.5, P = 0.61). Three patients had soft tissue infectious foci, with more intense <sup>18</sup>F-FDG uptake (SUV<sub>max</sub> 6.5 ± 2.5) than <sup>68</sup>Ga-citrate uptake (SUV<sub>max</sub> 3.9 ± 1.2, P = 0.0033). Conclusions. Our small cohort of patients with S. aureus bacteraemia revealed that <sup>68</sup>Ga-citrate PET/CT is comparable to <sup>18</sup>F-FDG PET/CT for detection of osteomyelitis, whereas <sup>18</sup>F-FDG resulted in a higher signal for the detection of soft tissue infectious foci.</p>...
Highlight selection of radiochemistry and radiopharmacy developments by editorial board (January-June 2020)
<p>Background<br></p><p>The Editorial Board of EJNMMI Radiopharmacy and Chemistry releases a biyearly highlight commentary to describe trends in the field.<br></p><p>Results<br></p><p>This commentary of highlights has ...