Viimeksi syötetyt Rinnakkaistallenteet
Aineistot 3121-3140 / 27094
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Comparative effectiveness of initial computed tomography and invasive coronary angiography in women and men with stable chest pain and suspected coronary artery disease: multicentre randomised trial
<p><strong>Objective: </strong>To assess the comparative effectiveness of computed tomography and invasive coronary angiography in women and men with stable chest pain suspected to be caused by coronary artery disease.</ ... -
Collagen prolyl 4-hydroxylase isoenzymes I and II have sequence specificity towards different X-Pro-Gly triplets
Collagen biosynthesis requires several co- and post-translational modifications of lysine and proline residues to form structurally and functionally competent collagen molecules. Formation of 4-hydroxyproline (4Hyp) in ... -
Mediated learning materials: visibility checks in telepresence robot mediated classroom interaction
Videoconferencing is increasingly used in education as a way to support distance learning. This article contributes to the emerging interactional literature on video-mediated educational interaction by exploring how a ... -
Thrombolysis treatment protected impairment of functional ability, quality of life and fatigue seven years after stroke
<p><strong>Objectives: </strong>We studied quality of life, functional outcome, depression, and fatigue of ischemic stroke patients treated with or without thrombolysis seven years post-stroke.</p><p><strong>Materials and ... -
Evaluation of renal glucose uptake with [18F]FDG-PET: Methodological advancements and metabolic outcomes
<p>Background/purpose<br>Studying renal glucose metabolism non-invasively in humans is an unmet need. Positron emission tomography (PET) is the current gold standard for measuring regional tissue glucose uptake rates, but ... -
The Growing Tide of Antiscience Sentiment: A Global Concern
<p>The growing tide of antiscience sentiment represents a critical global challenge, with particularly visible manifestations in the United States. This viewpoint examines how the rejection of scientific consensus threatens ... -
The exceptional VHE gamma-ray outburst of PKS 1510-089 in May 2016
<p>PKS 1510-089 (z=0.361) is one of only a handful of flat spectrum radio quasars that have been detected at very high energy (VHE, E > 100GeV) gamma rays. It is a very active source across the entire electromagnetic ... -
Endogenous PP2A inhibitor CIP2A degradation by chaperone-mediated autophagy contributes to the antitumor effect of mitochondrial complex I inhibition
<p>Combined inhibition of oxidative phosphorylation (OXPHOS) and glycolysis has been shown to activate a PP2A-dependent signaling pathway, leading to tumor cell death. Here, we analyze highly selective mitochondrial complex ... -
The plastidial protein acetyltransferase GNAT1 forms a complex with GNAT2, yet their interaction is dispensable for state transitions
Protein N-acetylation is one of the most abundant co- and post-translational modifications in eukaryotes, extending its occurrence to chloroplasts within vascular plants. Recently, a novel plastidial enzyme family comprising ... -
Varhaiskasvatuksen henkilöstön kokemuksia koronapandemian aiheuttamista muutoksista työssä keväällä 2020
<p>Koronavirustaudin (Covid-19) aiheuttama pandemia toi poikkeusolot myös suomalaiseen varhaiskasvatukseen maaliskuussa 2020. Tämän tutkimuksen tavoitteena on tuottaa tietoa siitä, miten varhaiskasvatuksen henkilöstö koki ... -
Utopia of Safe Air: How Soviet Research Challenged Western Air Quality Norms, 1950s-1960s
<p>During the mid-twentieth century, the Soviet Union developed ambitious hygiene standards for clean air that were grounded in extremely sensitive methods of physiological research. As Western experts sought to develop ... -
Novel plasma protein binding analysis method for a PET tracer and its radiometabolites: A case study with [11C]SMW139 to explain the high uptake of radiometabolites in mouse brain
Radiometabolites of PET tracers interfere with imaging and need to be taken into account when modeling PET data. Various tracer and radiometabolite characteristics affect the uptake rate into tissue. In this study, we ... -
Parental experiences and opinions regarding the management of acute otitis media in Finland—a comparative questionnaire between 2006 and 2019
<div><p><strong>Background</strong><br></p><p>Treatment guidelines for acute otitis media (AOM) have changed over the past 20 years. Watchful waiting is often recommended as an option for antibiotic treatment and the use ... -
The components of directional and disruptive selection in heterogeneous group-structured populations
We derive how directional and disruptive selection operate on scalar traits in a heterogeneous group-structured population for a general class of models. In particular, we assume that each group in the population can be ... -
Maturation of speech-elicited event-related potentials from birth to 28 months: Typical development with minor effects of dyslexia risk
<p>This study investigated in a longitudinal setting the maturation of obligatory auditory event-related potentials (ERPs) during infancy and early childhood, comparing the developmental patterns in infants with or without ... -
Sedentary time associates detrimentally and physical activity beneficially with metabolic flexibility in adults with metabolic syndrome
Metabolic flexibility (MetFlex) describes the ability to respond and adapt to changes in metabolic demand and substrate availability. The relationship between physical (in)activity and MetFlex is unclear. This study aimed ... -
Jetted narrow-line Seyfert 1 galaxies breaking the jet paradigm: A comprehensive study of host-galaxy morphologies
<p>Narrow-line Seyfert 1 (NLS1) galaxies are unevolved active galactic nuclei (AGNs) that exist predominantly in spiral galaxies. However, mostly due to the small number of sources studied, it has been under debate whether ...
