dc.contributor.author | Kankuri-Tammilehto Minna | |
dc.date.accessioned | 2022-10-27T12:13:26Z | |
dc.date.available | 2022-10-27T12:13:26Z | |
dc.identifier.uri | https://www.utupub.fi/handle/10024/157126 | |
dc.description.abstract | <p>Today we are increasingly interested in finding out the hereditary variants of moderate risk from a cancer patient. Multigene next generation sequencing (NGS) panel technology, massive parallel sequencing, can efficiently and economically analyze genes in 3 to 6 weeks. There are agreed criteria based on which to suspect hereditary breast cancer and thus to make a referral to clinical genetic unit. The topic research subject is to investigate the cancer risk associated with moderate risk genes. Appropriate follow-up recommendations for persons with moderate genetic susceptibility pathogenic variants to breast cancer are updated regularly as scientific research is published. This is a case report on two <em>CHEK2</em> families in which pathogenic variant in <em>CHEK2</em> gene does not alone explain the breast cancer risk of the patients. This is also a mini review of genetic susceptibility of <em>CHEK2</em> moderate breast cancer gene.<br></p> | |
dc.language.iso | en | |
dc.publisher | JSciMedCentral | |
dc.title | Genetic Susceptibility due to Moderate Breast Cancer Risk Gene CHEK2: a case report | |
dc.identifier.url | https://www.jscimedcentral.com/Oncology/oncology-9-1065.pdf | |
dc.identifier.urn | URN:NBN:fi-fe2022012710598 | |
dc.relation.volume | 9 | |
dc.contributor.organization | fi=tyks, vsshp|en=tyks, vsshp| | |
dc.contributor.organization | fi=biolääketieteen laitos, yhteiset|en=Institute of Biomedicine| | |
dc.contributor.organization-code | 2607100 | |
dc.converis.publication-id | 68751544 | |
dc.converis.url | https://research.utu.fi/converis/portal/Publication/68751544 | |
dc.identifier.eissn | 2373-938X | |
dc.identifier.jour-issn | 2373-938X | |
dc.okm.affiliatedauthor | Dataimport, tyks, vsshp | |
dc.okm.affiliatedauthor | Kankuri-Tammilehto, Minna | |
dc.okm.discipline | 3111 Biolääketieteet | fi_FI |
dc.okm.discipline | 3111 Biomedicine | en_GB |
dc.okm.internationalcopublication | not an international co-publication | |
dc.okm.internationality | International publication | |
dc.okm.type | B1 Non-refereed journal articles | |
dc.publisher.country | United States | en_GB |
dc.publisher.country | Yhdysvallat (USA) | fi_FI |
dc.publisher.country-code | US | |
dc.relation.articlenumber | 1065 | |
dc.relation.ispartofjournal | Journal of Clinical Oncology and Research | |
dc.relation.issue | 1 | |
dc.year.issued | 2021 | |