A survey on thromboprophylaxis and coagulation assessment in children and young adults with acute lymphoblastic leukaemia (ALL) in the Nordic and Baltic countries: Different practices of assessment and management
Lohi Olli; Jarvis Kirsten Brunswig; Molle Ingolf; Ranta Susanna; Långström Satu; Overgaard Ulrik; Rathe Mathias; Vepsäläinen Kaisa; Vogt Harmut; Albertsen Birgitte K; Andersson Nadine G; Huurre Anu; Hoffmann Marianne; Joelsson Joel; Trakymiene Sonata Saulyte
A survey on thromboprophylaxis and coagulation assessment in children and young adults with acute lymphoblastic leukaemia (ALL) in the Nordic and Baltic countries: Different practices of assessment and management
Lohi Olli
Jarvis Kirsten Brunswig
Molle Ingolf
Ranta Susanna
Långström Satu
Overgaard Ulrik
Rathe Mathias
Vepsäläinen Kaisa
Vogt Harmut
Albertsen Birgitte K
Andersson Nadine G
Huurre Anu
Hoffmann Marianne
Joelsson Joel
Trakymiene Sonata Saulyte
WILEY
Julkaisun pysyvä osoite on:
https://urn.fi/URN:NBN:fi-fe2022091258529
https://urn.fi/URN:NBN:fi-fe2022091258529
Tiivistelmä
Patients undergoing treatment for acute lymphoblastic leukaemia (ALL) are at risk of coagulopathy, especially thromboembolism. We conducted a survey on practices in the assessment and management of coagulopathy during the new ALLTogether protocol in 29 (17 paediatric, 12 adult) Nordic and Baltic cancer centres. While 92% of adult centres used thromboprophylaxis with low-molecular-weight heparin, no paediatric centre did. Almost all providers performed baseline coagulation studies, but only 59% continued the assessment. Fibrinogen replacement was conducted in 59%, and antithrombin replacement in 28% of the centres. The survey highlights the need for guidelines in the management of coagulopathy during ALL therapy.
Kokoelmat
- Rinnakkaistallenteet [19207]