Näytä suppeat kuvailutiedot

The effect of nanodiamonds on candida albicans adhesion and surface characteristics of PMMA denture base material - an in vitro study

Passent Ellakany; Ahmad M. Al-Thobity; Fahad A. Al-Harbi; Jorma I. Virtanen; Shaimaa M. Fouda; Mohammed M. Gad; Aune Raustia

dc.contributor.authorPassent Ellakany
dc.contributor.authorAhmad M. Al-Thobity
dc.contributor.authorFahad A. Al-Harbi
dc.contributor.authorJorma I. Virtanen
dc.contributor.authorShaimaa M. Fouda
dc.contributor.authorMohammed M. Gad
dc.contributor.authorAune Raustia
dc.date.accessioned2022-10-28T12:32:58Z
dc.date.available2022-10-28T12:32:58Z
dc.identifier.urihttps://www.utupub.fi/handle/10024/160318
dc.description.abstract<p>Candida albicans is the main causative pathogen of denture stomatitis, which affects many complete denture patients. Objective: To evaluate the effect of different concentrations of nanodiamonds (NDs) added to polymethyl methacrylate (PMMA) denture base material on Candida albicans adhesion as well as on surface roughness and contact angle. Methodology: Acrylic resin specimens sized 10×10×3 mm3 were prepared and divided into four groups (n=30) according to ND concentration (0%, 0.5%, 1%, 1.5% by wt). Surface roughness was measured with a profilometer, and the contact angle with a goniometer. The effect of NDs on Candida albicans adhesion was evaluated using two methods: 1) slide count and 2) direct culture test. Analysis of variance (ANOVA) and Tukey’s post hoc test were used in the statistical analyses. Results: Addition of NDs decreased the Candida albicans count significantly more than in the control group (p<0.05), with a lowest of 1% NDs. Addition of NDs also significantly decreased the surface roughness (p<0.05), but the contact angle remained the same. Incorporation of NDs into the PMMA denture base material effectively reduced Candida albicans adhesion and decreased surface roughness. Conclusion: PMMA/NDs composites could be valuable in the prevention of denture stomatitis, which is considered one of the most common clinical problems among removable denture wearers.<br /></p>
dc.language.isoen
dc.titleThe effect of nanodiamonds on candida albicans adhesion and surface characteristics of PMMA denture base material - an in vitro study
dc.identifier.url10.1590/1678-7757-2018-0779
dc.identifier.urnURN:NBN:fi-fe2021042825124
dc.relation.volume27
dc.contributor.organizationfi=hammaslääketieteen laitos yhteiset|en=Institute of Dentistry|
dc.contributor.organization-code2607500
dc.converis.publication-id44443338
dc.converis.urlhttps://research.utu.fi/converis/portal/Publication/44443338
dc.identifier.eissn1678-7757
dc.identifier.jour-issn1678-7757
dc.okm.affiliatedauthorVirtanen, Jorma
dc.okm.discipline313 Dentistryen_GB
dc.okm.discipline313 Hammaslääketieteetfi_FI
dc.okm.internationalcopublicationinternational co-publication
dc.okm.internationalityInternational publication
dc.okm.typeJournal article
dc.relation.doi10.1590/1678-7757-2018-0779
dc.relation.ispartofjournalJournal of Applied Oral Science
dc.year.issued2019


Aineistoon kuuluvat tiedostot

Thumbnail

Aineisto kuuluu seuraaviin kokoelmiin

Näytä suppeat kuvailutiedot