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Drug Target Commons 2.0: a community platform for systematic analysis of drug target interaction profiles

Markus Vähä-Koskela; Tero Aittokallio; Alina Malyutina; Zaid Alam; Balaguru Ravikumar; Jing Tang; Ziaur Rehman Tanoli; Krister Wennerberg; Alok Jaiswal
dc.contributor.authorMarkus Vähä-Koskela
dc.contributor.authorTero Aittokallio
dc.contributor.authorAlina Malyutina
dc.contributor.authorZaid Alam
dc.contributor.authorBalaguru Ravikumar
dc.contributor.authorJing Tang
dc.contributor.authorZiaur Rehman Tanoli
dc.contributor.authorKrister Wennerberg
dc.contributor.authorAlok Jaiswal
dc.date.accessioned2022-10-28T13:02:35Z
dc.date.available2022-10-28T13:02:35Z
dc.identifier.urihttps://www.utupub.fi/handle/10024/162394
dc.description.abstractDrug Target Commons (DTC) is a web platform (database with user interface) for community-driven bioactivity data integration and standardization for comprehensive mapping, reuse and analysis of compound-target interaction profiles. End users can search, upload, edit, annotate and export expert-curated bioactivity data for further analysis, using an application programmable interface, database dump or tab-delimited text download options. To guide chemical biology and drug-repurposing applications, DTC version 2.0 includes updated clinical development information for the compounds and target gene-disease associations, as well as cancer-type indications for mutant protein targets, which are critical for precision oncology developments.
dc.language.isoen
dc.publisherOXFORD UNIV PRESS
dc.titleDrug Target Commons 2.0: a community platform for systematic analysis of drug target interaction profiles
dc.identifier.urlhttps://academic.oup.com/database/article/doi/10.1093/database/bay083/5096727
dc.identifier.urnURN:NBN:fi-fe2021042719927
dc.contributor.organizationfi=tilastotiede|en=Statistics|
dc.contributor.organizationfi=Turun luonnontieteiden ja lääketieteen tutkijakollegium (TCSM)|en=Turku Collegium for Science and Medicine (TCSM)|
dc.contributor.organizationfi=matematiikka|en=Mathematics|
dc.contributor.organization-code2606103
dc.contributor.organization-code2606101
dc.converis.publication-id36126986
dc.converis.urlhttps://research.utu.fi/converis/portal/Publication/36126986
dc.identifier.eissn1758-0463
dc.identifier.jour-issn1758-0463
dc.okm.affiliatedauthorAittokallio, Tero
dc.okm.affiliatedauthorDataimport, LLK:n yhteiset
dc.okm.affiliatedauthorTang, Jing
dc.okm.discipline317 Pharmacyen_GB
dc.okm.discipline3122 Cancersen_GB
dc.okm.discipline317 Farmasiafi_FI
dc.okm.discipline3111 Biolääketieteetfi_FI
dc.okm.discipline111 Mathematicsen_GB
dc.okm.discipline112 Tilastotiedefi_FI
dc.okm.discipline3111 Biomedicineen_GB
dc.okm.discipline112 Statistics and probabilityen_GB
dc.okm.discipline111 Matematiikkafi_FI
dc.okm.discipline3122 Syöpätauditfi_FI
dc.okm.internationalcopublicationinternational co-publication
dc.okm.internationalityInternational publication
dc.okm.typeJournal article
dc.publisher.countryBritanniafi_FI
dc.publisher.countryUnited Kingdomen_GB
dc.publisher.country-codeGB
dc.relation.articlenumberARTN bay083
dc.relation.doi10.1093/database/bay083
dc.relation.ispartofjournalDatabase: The Journal of Biological Databases and Curation
dc.relation.issue1
dc.year.issued2018


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