Predicting the Need for Biopsy to Detect Clinically Significant Prostate Cancer in Patients with a Magnetic Resonance Imaging–detected Prostate Imaging Reporting and Data System/Likert ≥3 Lesion: Development and Multinational External Validation of the Imperial Rapid Access to Prostate Imaging and Diagnosis Risk Score
Falagario U.G.; Reddy D.; Picker W.; Cucchiara V.; Stabile A.; Eldred-Evans D.; Bass E.; Gordon S.; Ahmed H.U.; Taimen P.; van Rossum P.S.N.; Verhoeff J.J.C.; Martini A.; Montoya Perez I.; Boström P.J.; Nordström T.; Wong K.; Aronen H.J.; Knaapila J.; Lantz A.; Connor M.J.; Peters M.; Qazi H.; Kurver P.; Gandaglia G.; Briganti A.; Shah T.T.; Winkler M.; Tam H.; Jambor I.; Ettala O.; Haug E.S.; Fossati N.; Tanaka M.B.
Predicting the Need for Biopsy to Detect Clinically Significant Prostate Cancer in Patients with a Magnetic Resonance Imaging–detected Prostate Imaging Reporting and Data System/Likert ≥3 Lesion: Development and Multinational External Validation of the Imperial Rapid Access to Prostate Imaging and Diagnosis Risk Score
Falagario U.G.
Reddy D.
Picker W.
Cucchiara V.
Stabile A.
Eldred-Evans D.
Bass E.
Gordon S.
Ahmed H.U.
Taimen P.
van Rossum P.S.N.
Verhoeff J.J.C.
Martini A.
Montoya Perez I.
Boström P.J.
Nordström T.
Wong K.
Aronen H.J.
Knaapila J.
Lantz A.
Connor M.J.
Peters M.
Qazi H.
Kurver P.
Gandaglia G.
Briganti A.
Shah T.T.
Winkler M.
Tam H.
Jambor I.
Ettala O.
Haug E.S.
Fossati N.
Tanaka M.B.
Elsevier B.V.
Julkaisun pysyvä osoite on:
https://urn.fi/URN:NBN:fi-fe2022102463098
https://urn.fi/URN:NBN:fi-fe2022102463098
Tiivistelmä
Background: Although multiparametric magnetic resonance imaging (MRI) has high
sensitivity, its lower specificity leads to a high prevalence of false-positive lesions requir-
ing biopsy.
Objective: To develop and externally validate a scoring system for MRI-detected Prostate
Imaging Reporting and Data System (PIRADS)/Likert 3 lesions containing clinically sig-
nificant prostate cancer (csPCa).
Design, setting, and participants: The multicentre Rapid Access to Prostate Imaging and
Diagnosis (RAPID) pathway included 1189 patients referred to urology due to elevated
age-specific prostate-specific antigen (PSA) and/or abnormal digital rectal examination (DRE); April 27, 2017 to October 25, 2019.
Kokoelmat
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