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Predicting the Need for Biopsy to Detect Clinically Significant Prostate Cancer in Patients with a Magnetic Resonance Imaging–detected Prostate Imaging Reporting and Data System/Likert ≥3 Lesion: Development and Multinational External Validation of the Imperial Rapid Access to Prostate Imaging and Diagnosis Risk Score

Peters Max; Eldred-Evans David; Kurver Piet; Falagario Ugo Giovanni; Connor Martin J.; Shah Taimur T.; Verhoeff Joost J.C.; Taimen Pekka; Aronen Hannu J.; Knaapila Juha; Montoya Perez Ileana; Ettala Otto; Stabile Armando; Gandaglia Giorgio; Fossati Nicola; Martini Alberto; Cucchiara Vito; Briganti Alberto; Lantz Anna; Picker Wolfgang; Haug Erik Skaaheim; Nordström Tobias; Tanaka Mariana Bertoncelli; Reddy Deepika; Bass Edward; van Rossum Peter S.N.; Wong Kathie; Tam Henry; Winkler Mathias; Gordon Stephen; Qazi Hasan; Boström Peter J.; Jambor Ivan; Ahmed Hashim U.

Predicting the Need for Biopsy to Detect Clinically Significant Prostate Cancer in Patients with a Magnetic Resonance Imaging–detected Prostate Imaging Reporting and Data System/Likert ≥3 Lesion: Development and Multinational External Validation of the Imperial Rapid Access to Prostate Imaging and Diagnosis Risk Score

Peters Max
Eldred-Evans David
Kurver Piet
Falagario Ugo Giovanni
Connor Martin J.
Shah Taimur T.
Verhoeff Joost J.C.
Taimen Pekka
Aronen Hannu J.
Knaapila Juha
Montoya Perez Ileana
Ettala Otto
Stabile Armando
Gandaglia Giorgio
Fossati Nicola
Martini Alberto
Cucchiara Vito
Briganti Alberto
Lantz Anna
Picker Wolfgang
Haug Erik Skaaheim
Nordström Tobias
Tanaka Mariana Bertoncelli
Reddy Deepika
Bass Edward
van Rossum Peter S.N.
Wong Kathie
Tam Henry
Winkler Mathias
Gordon Stephen
Qazi Hasan
Boström Peter J.
Jambor Ivan
Ahmed Hashim U.
Katso/Avaa
Taimen_etAl2022_Article_PredictingtheNeedforBiopsy.pdf (1.759Mb)
Lataukset: 

Elsevier B.V.
doi:10.1016/j.eururo.2022.07.022
URI
https://doi.org/10.1016/j.eururo.2022.07.022
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Julkaisun pysyvä osoite on:
https://urn.fi/URN:NBN:fi-fe2022102463098
Tiivistelmä

Background: Although multiparametric magnetic resonance imaging (MRI) has high
sensitivity, its lower specificity leads to a high prevalence of false-positive lesions requir-
ing biopsy.
Objective: To develop and externally validate a scoring system for MRI-detected Prostate
Imaging Reporting and Data System (PIRADS)/Likert 3 lesions containing clinically sig-
nificant prostate cancer (csPCa).
Design, setting, and participants: The multicentre Rapid Access to Prostate Imaging and
Diagnosis (RAPID) pathway included 1189 patients referred to urology due to elevated
age-specific prostate-specific antigen (PSA) and/or abnormal digital rectal examination (DRE); April 27, 2017 to October 25, 2019.

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