Adaptation of bacteria to glyphosate: a microevolutionary perspective of the enzyme 5-enolpyruvylshikimate-3-phosphate synthase
Puigbò Pere; Rainio Miia J; Saloniemi Irma; Helander Marjo; Ruuskanen Suvi; Saikkonen Kari
Adaptation of bacteria to glyphosate: a microevolutionary perspective of the enzyme 5-enolpyruvylshikimate-3-phosphate synthase
Puigbò Pere
Rainio Miia J
Saloniemi Irma
Helander Marjo
Ruuskanen Suvi
Saikkonen Kari
WILEY
Julkaisun pysyvä osoite on:
https://urn.fi/URN:NBN:fi-fe2021042826711
https://urn.fi/URN:NBN:fi-fe2021042826711
Tiivistelmä
Glyphosate is the leading herbicide worldwide, but it also affects prokaryotes because it targets the central enzyme (5-enolpyruvylshikimate-3-phosphate, EPSP) of the shikimate pathway in the synthesis of the three essential aromatic amino acids in bacteria, fungi and plants. Our results reveal that bacteria may easily become resistant to glyphosate through changes in the 5-enolpyruvylshikimate-3-phosphate synthase active site. This indicates the importance of examining how glyphosate affects microbe-mediated ecosystem functions and human microbiomes.
Kokoelmat
- Rinnakkaistallenteet [19176]