Preconceptual leptin levels in gestational diabetes and hypertensive pregnancy
Kaaja Risto; Lisinen Irina; Viikari Liisa; Peltokorpi Antti
https://urn.fi/URN:NBN:fi-fe2022081154347
Tiivistelmä
Pregnancy - induced hypertension (PIH), preeclampsia (PE), and gestational diabetes (GDM) are common adverse outcomes in pregnancy.
Objective
To find out whether preconceptual leptin levels differ in subsequent pregnancy between control vs. GDM and hypertensive pregnancy groups.
Materials and Methods
Data was from The Cardiovascular Risk in Young Finns Study and The Medical Birth Register of Finland. Of 293 subjects 71 developed GDM, 27 PIH/PE and 201 were controls.
Results
Leptin was higher in GDM (p < 0.0001) and PIH/PE (p = 0.0002) groups compared to control. GDM group was robust to BMI matching (p = 0,0081).
Conclusion
Leptin was higher in GDM (p < 0.0001) and PIH/PE (p = 0.0002) groups compared to control. GDM group was robust to BMI matching (p = 0,0081).
Kokoelmat
- Rinnakkaistallenteet [19207]