Occurrence and mortality of vasospastic angina pectoris hospitalised patients in Finland: a population-based registry cohort study
Jussi Sipilä; Päivi Rautava; Ville Kytö; Juuso Blomster; Essi Pikkarainen
https://urn.fi/URN:NBN:fi-fe2021042824456
Tiivistelmä
OBJECTIVES:
The occurrence and mortality of vasospastic
angina pectoris (VAP) is largely unknown in western countries. Our
objective was to clarify the occurrence, gender-distribution and
mortality of VAP in Finland using a population-based hospital registry.
METHODS:
We
studied consecutive patients aged ≥18 years hospitalized with VAP as
the primary cause of admission in Finland during 2004-2014. The data
were collected from obligatory nationwide registries. During the study
period 1762 admissions were recorded.
RESULTS:
Majority
of all VAP patients were male (59.7%) and mean age was 65.7±12.0 years.
Annual admission rate for VAP was 2.29/100 000 person-years. Men were in
higher risk for VAP than women (admission rate 3.00/100 000 vs
1.68/100 000; RR 1.70; p<0.0001). Gender difference was not modified
by age. Likelihood of VAP was highest in population aged 70-84 years.
Admission rate for VAP decreased notably during the study period.
One-year all-cause mortality was 8.0% and 3-year mortality was 15.5%
(cardiac mortality 11.1%). Mortality was associated with increasing age,
comorbidity burden and lack of detected coronary artery obstruction,
but was similar between genders and during the study period.
CONCLUSIONS:
Men
have higher risk for vasospastic angina caused admissions. Likelihood
of vasospastic angina admission was highest in aged population. The
3-year all-cause mortality was 15.5%. Mortality was associated with
increasing age, comorbidities and non-obstructive VAP diagnosis but was
similar between genders.
Kokoelmat
- Rinnakkaistallenteet [19207]