Global Distribution of Human Protoparvoviruses
Dufton Mwaengo; Ushanandini Mohanraj; Maria Söderlund-Venermo; Klaus Hedman; Moses Masika; Paula M. Kinnunen1; Haider Al-Hello; Amir Majlesi; Omu Anzala; Ali M. Barakat; Eric Delwart; Olli Vapalahti; Pikka Jokelainen; Mohammadreza Sadeghi; Farid A. Jalilian; Elina Väisänen
Global Distribution of Human Protoparvoviruses
Dufton Mwaengo
Ushanandini Mohanraj
Maria Söderlund-Venermo
Klaus Hedman
Moses Masika
Paula M. Kinnunen1
Haider Al-Hello
Amir Majlesi
Omu Anzala
Ali M. Barakat
Eric Delwart
Olli Vapalahti
Pikka Jokelainen
Mohammadreza Sadeghi
Farid A. Jalilian
Elina Väisänen
CENTERS DISEASE CONTROL
Julkaisun pysyvä osoite on:
https://urn.fi/URN:NBN:fi-fe2021042719451
https://urn.fi/URN:NBN:fi-fe2021042719451
Tiivistelmä
Development of next-generation sequencing and metagenomics has revolutionized detection of novel viruses. Among these viruses are 3 human protoparvoviruses: bufavirus, tusavirus, and cutavirus. These viruses have been detected in feces of children with diarrhea. In addition, cutavirus has been detected in skin biopsy specimens of cutaneous T-cell lymphoma patients in France and in 1 melanoma patient in Denmark. We studied seroprevalences of IgG against bufavirus, tusavirus, and cutavirus in various populations (n = 840), and found a striking geographic difference in prevalence of bufavirus IgG. Although prevalence was low in adult populations in Finland (1.9%) and the United States (3.6%), bufavirus IgG was highly prevalent in populations in Iraq (84.8%), Iran (56.1%), and Kenya (72.3%). Conversely, cutavirus IgG showed evenly low prevalences (0%-5.6%) in all cohorts, and tusavirus IgG was not detected. These results provide new insights on the global distribution and endemic areas of protoparvoviruses.
Kokoelmat
- Rinnakkaistallenteet [19207]