Finnish children carrying the high-risk HLA genotype have a 45-fold increased risk of type 1 diabetes compared to peers with neutral or protective genotypes

Taka Antti-Mathias; But Anna; Lempainen Johanna; Vatanen Tommi; Härkönen Taina; Ilonen Jorma; Knip Mikael
Finnish children carrying the high-risk HLA genotype have a 45-fold increased risk of type 1 diabetes compared to peers with neutral or protective genotypes

Taka Antti-Mathias
But Anna
Lempainen Johanna
Vatanen Tommi
Härkönen Taina
Ilonen Jorma
Knip Mikael
Katso/Avaa
Lataukset: 

Elsevier
doi:10.1016/j.diabres.2023.110256
URI
https://doi.org/10.1016/j.diabres.2023.110256
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Julkaisun pysyvä osoite on:
https://urn.fi/URN:NBN:fi-fe2023032933667
Tiivistelmä
The association between HLA genotypes and type 1 diabetes is well known. We set out to examine incidence rates and ratios of type 1 diabetes depending on the risk afflicted by HLA genotype. Children with the high-risk genotype have a 45-fold disease risk compared to peers with neutral or protective genotypes.
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