Generation of two human induced pluripotent stem cell lines from peripheral blood mononuclear cells featuring normal or mutated STAB1 gene

Sandelin, Sanne; Giannareas, Nikolaos; Kere, Juha; Seppänen, Mikko R. J.; Hollmen, Maija; Närvä, Elisa
Generation of two human induced pluripotent stem cell lines from peripheral blood mononuclear cells featuring normal or mutated STAB1 gene

Sandelin, Sanne
Giannareas, Nikolaos
Kere, Juha
Seppänen, Mikko R. J.
Hollmen, Maija
Närvä, Elisa
Katso/Avaa
Lataukset: 

Elsevier
doi:10.1016/j.scr.2025.103750
URI
https://doi.org/10.1016/j.scr.2025.103750
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Julkaisun pysyvä osoite on:
https://urn.fi/URN:NBN:fi-fe2025082792830
Tiivistelmä

Here, we report the establishment of a human induced pluripotent stem cell (hiPSC) line TUR-STAB1-B1 derived from peripheral blood mononuclear cells of a patient carrying heterozygous mutations 52,509,890 C>A 790L>I and 52,520,515 G>A 1872R>H on STAB1 gene in addition to a normal control cell line TUR-B1. The pluripotency, identity, quality, safety, and sequence of the mutation sites of the cell lines were confirmed. The generated patient-specific cell line will facilitate detailed studies of the STAB1 in various differentiated cell types.

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