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Phage display based approach for identifying novel HDL particle binders: Recombinant HDL antibodies as novel diagnostic tool for risk assessment and monitoring of coronary artery disease
(Turun yliopisto, 2022-11-11)
Cholesterol content of high density lipoprotein (HDL-C) has been a well established cardiac risk marker for coronary artery disease (CAD), a major cause of mortality worldwide. Various epidemiological and experimental ...
Cardiac Troponin Specific Autoantibodies: Analytical Tools for Exploring Their Impact on Cardiac Troponin I Testing
(Turun yliopistoAnnales Universitatis Turkuensis A II 293, 2014-10-17)
Cardiac troponin (cTn) I and T are the recommended biomarkers for the diagnosis and risk stratification of patients with suspected acute coronary syndrome (ACS), a major cause of cardiovascular death and disability worldwide. ...
Upconverting nanoparticles in bioaffinity assays : new insights and perspectives
(Turun yliopisto, 2019-10-18)
Photon upconverting nanoparticles (UCNPs) are promising reporters for supersensitive bioaffinity assays because they can be detected completely without autofluorescence background. This is enabled by anti-Stokes shifted ...
Diagnostic and prognostic value of free PAPP-A in coronary artery disease – clinical studies with novel immunoassay
(Turun yliopisto, 2022-12-09)
Complications of coronary artery disease are the number one cause of death worldwide, so identification of high-risk individuals is crucial. Pregnancy-associated plasma protein A (PAPP-A) is a candidate cardiac-risk related ...