Hae
Aineistot 1-10 / 20
Genomic comparisons of carbonic anhydrase V genes in vertebrates
(Turun yliopisto, 2018-07-11)
Carbonic anhydrases are involved in many processes of life, have been discovered in every living organism, and are widely distributed in tissues. Carbonic anhydrases are involved in different biochemical processes, such ...
Analysis of the Phosphoproteome of Jnk1-/- vs Wild Type Mouse Brain Provides Novel Insight on JNK1's Interaction Profile and Its Connection to Various Mental Disorders
(Turun yliopisto, 2018-03-05)
c-Jun N-terminal kinases (JNKs) are multifunctional kinases that are involved in various diseases. The JNK pathway plays a major role in cell death in response to a variety of stimuli; it hence plays a part in diseases ...
Comparison of peptide peak intensity methods for label free relative protein quantification
(Turun yliopisto, 2018-02-21)
During the recent years, Liquid chromatography-mass spectrometry (LC-MS) has gained enormous attention to identify and quantify peptides in biological samples. The Current challenge is to quantify the level of proteins as ...
Computational inference of functional relationships from multiple genomes : Drosophila carbonic anhydrases.
(Turun yliopisto, 2018-09-24)
Carbonic anhydrases (CAHs) are metalloenzymes which catalyze the reversible chemical reaction
between carbon dioxide and water to bicarbonate and a proton, which is crucial in pH homeostasis.
There are several CAH families ...
Machine Learning Methods for the Classification of Endometriosis
(Turun yliopisto, 2018-03-05)
Endometriosis is a benign disorder estimated to affect 10% of women during their reproductive years. The main method for the diagnosis of endometriosis currently used by the clinicians is laparoscopic inspection followed ...
Comparison of five popular normalization methods using a spike-in proteomics data set
(Turun yliopisto, 2016-08-18)
Mass spectrometry (MS)-based proteomics has seen significant technical advances during the past two decades and mass spectrometry has become a central tool in many biosciences. Despite the popularity of MS-based methods, ...
Probing MST1 Kinase Sequence and Structure for Rational Drug Discovery (Targeting diabetes by blocking protein-protein interactions)
(Turun yliopisto, 2016-04-26)
Apoptotic beta cell death is an underlying cause majorly for type I and to a lesser extent for type II diabetes. Recently, MST1 kinase was identified as a key apoptotic agent in diabetic condition. In this study, I have ...
Human Ezrin: Prediction of the 3D structure and interactions with mTOR
(Turun yliopisto, 2016-06-15)
The protein Ezrin, is a member of the ERM family (Ezrin, Radixin and Moesin) that links the F-actin to the plasma membrane. The protein is made of three domains namely the FERM domain, a central α-helical domain and the ...
Phylogenetic Analysis of Avidins and Expression of Novel Avidins from Lactrodectus hesperus and Hoeflea phototrophica
(Turun yliopisto, 2015-11-05)
Avidins (Avds) are homotetrameric or homodimeric glycoproteins with typically less than 130 amino acid residues per monomer. They form a highly stable, non-covalent complex with biotin (vitamin H) with Kd = 10-15 M (for ...
Adopting the Vaadin Java framework to rebuild VTT’s Web Interfaces and Database Applications
(Turun yliopisto, 2015-12-14)
With the growth in new technologies, using online tools have become an everyday lifestyle. It has a greater impact on researchers as the data obtained from various experiments needs to be analyzed and knowledge of programming ...