Hae
Aineistot 11-20 / 30
Tissue-specific insulin sensitivity in humans - with special reference to the liver
(Turun yliopisto, 2019-03-09)
The number of individuals affected by Type 2 diabetes mellitus (T2DM) is increasing rapidly nearly everywhere in the world. Insulin resistance, which means reduced impact of insulin in its target tissues, especially in the ...
Effect of bariatric surgery on liver metabolism -studies using positron emission tomography
(Turun yliopisto, 2019-04-27)
Obesity is a significant and increasing health challenge. Obesity is strongly associated with the incidence of type 2 diabetes (T2D). In obese individuals, liver insulin resistance is a major factor in the development and ...
Regulation of intestinal metabolism in obesity and diabetes : studies using positron emission tomography
(Turun yliopisto, 2018-06-01)
The global epidemic of obesity is a challenge to healthcare systems due to the increase in the incidence of type 2 diabetes (T2D) and its associated morbidities. Although the small intestine is the first absorptive organ ...
Phenotypic and genetic subtyping of hypertension – toward personalized hypertension care
(Turun yliopisto, 2022-11-04)
Current knowledge of phenotypic and genotypic hypertension risk factors has not been effectively translated into personalized hypertension care. The aim of this thesis was to explore hypertension subtyping by applying ...
Metabolomics and metagenomics in hypertension
(Turun yliopisto, 2022-06-10)
While hypertension has been linked to various modifiable and fixed risk factors, the exact mechanisms behind blood pressure (BP) regulation and hypertension onset remain elusive. The rapid development in scientific branches ...
Heart failure – risk factors and the validity of diagnoses
(Turun yliopisto, 2022-08-19)
Heart failure (HF) is a global health problem. HF risk factors remain understudied. The roles that diabetes and sodium consumption play in HF remain unknown. Furthermore, the validity of HF diagnoses in the Finnish Hospital ...
Diagnostic challenges in the evaluation of renal osteodystrophy – A Study using 18F-sodium fluoride positron emission tomography
(Turun yliopisto, 2022-04-22)
The majority of patients with end-stage kidney disease develop abnormalities in bone metabolism, referred to as renal osteodystrophy. Bone abnormalities are associated with cardiovascular morbidity and mortality. The ...
Predictors of cardiovascular disease and mortality in patients with advanced chronic kidney disease
(Turun yliopisto, 2022-05-20)
Cardiovascular disease is the leading cause of high mortality in advanced chronic kidney disease (CKD) patients. Treatment and prevention of cardiovascular disease should be in focus to improve prognosis in this high-risk ...
Improved diagnostic accuracy for hypertension
(Turun yliopisto, 2020-06-27)
Practical and accurate blood pressure (BP) measurement techniques are needed to ensure adequate diagnostics and treatment of hypertension. Recently, novel monitors have appeared on the market including timer-equipped home ...
Vascular function in kidney transplant recipients and in patients with renovascular disease
(Turun yliopisto, 2021-10-29)
Cardiovascular mortality is 20 times higher in patients with chronic kidney disease and 3─5 times higher in patients with a kidney transplant than in the age-matched general population, which is partly explained by endothelial ...