Hae
Aineistot 11-20 / 22
Liikunnan vaikutus veren lipidiarvoihin
(Turun yliopisto, 2018-03-19)
Tämän tutkielman aiheena ovat elimistön lipidiaineenvaihdunta sekä dyslipidemiat ja liikunnan vaikutukset niihin. Kyseessä on kirjallisuuskatsaus, jonka tarkoituksena on koota yhteen tietoa tuoreimmista meta-analyyseistä ...
Outcome of Hsd17b1 gene deletion in ovarian and adipose tissue function : alterations resulting from both HSD17B1 enzyme inhibition and the off-target effect on the Naglu gene
(Turun yliopisto, 2018-01-05)
Steroids comprise a group of hormones that are, in the traditional view, secreted by the adrenal cortex, testes and ovaries, as well as the placenta during pregnancy and that reach their target organs via blood circulation. ...
Targeting Somatostatin Receptors with Peptide-functionalized Silica Nanoparticles
(Turun yliopisto, 2021-08-25)
ABSTRACT
Nano-sized synthetic drug carriers comprise a valuable addition to oncology armaments, opening new avenues for improved delivery of anticancer therapies. Nanocarriers designed to bind surface receptors of tumor ...
Uncovering the role of DICER and pericentric heterochromatin expression during spermatogenesis
(Turun yliopisto, 2020-10-30)
Male germ cell differentiation is a complex process that includes mitotic proliferation, meiosis and haploid differentiation phase, during which the cell undergoes dramatic morphological changes to produce mature spermatozoa. ...
Old acquaintances and new perspectives into testicular development and function
(Turun yliopisto, 2020-11-27)
Testicular development and function are complex processes that involve synchronization of the proliferation, apoptosis, and differentiation of specific somatic and germ cells to ensure lifelong fertility. Dysregulation of ...
Function of Germline-specific Ribonucleoprotein granules-from germline to cancer
(Turun yliopisto, 2023-12-15)
Male germ cells undergo complex differentiation from embryonic germ cells, through postnatal spermatogenesis to highly specialized spermatozoa. Precise regulation of gene expression is critical for meiosis and morphological ...
Developmental aspects of male reproductive health: clinical studies on semen quality, cryptorchidism, and puberty
(Turun yliopisto, 2023-08-11)
Current evidence shows increasing rates of male reproductive disorders, including cryptorchidism, hypospadias, poor semen quality, decreased testosterone level, and testicular cancer. Therefore, studies on the physiology ...
Tools and strategies for RNA-sequencing data analysis
(Turun yliopisto, 2023-08-25)
RNA-Sequencing (RNA-seq) has enabled the in-depth study of the transcriptome, becoming the primary research method in the field of molecular biology. The typical aim of RNA-seq is to quantify and detect differentially ...
HSD17BS in steroid and lipid metabolism and lipid disorders: the role of HSD17B12 and HSD17B13
(Turun yliopisto, 2023-10-27)
ABSTRACT
Non-alcoholic fatty liver disease (NAFLD), characterized by the accumulation of fat within hepatocytes, has become the most common chronic liver disease in developed countries. NAFLD is associated with insulin ...
The Ins and outs of the chromatoid body
(Turun yliopisto, 2023-10-13)
Spermatogenesis is a complex differentiation process that produces millions of genetically unique sperm cells every day. During spermatogenesis the developing germ cells undergo metamorphic changes as they transform from ...