Hae
Aineistot 221-229 / 229
Nature’s brewery to bedtime: The Role of hops in GABAA receptor modulation and sleep promotion
(Turun yliopisto, 2024-01-12)
Insomnia, a prevalent health challenge, often requires pharmacological interventions to improve sleep onset, maintenance, and quality. Benzodiazepines and Z-drugs, like other positive modulators, enhance the inhibitory ...
Premature ejaculation - potential role of α2-adrenoceptor agonists for symptomatic treatment. Studies of dexmedetomidine, fadolmidine and tasipimidine
(Turun yliopisto, 2024-04-26)
Ejaculation is a physiological process that results in the expulsion of semen from the male reproduction tract during a sexual climax and is considered an essential component of natural conception. Ejaculation is a delicately ...
Characteristics of anti-pertussis toxin antibodies after vaccination and infection
(Turun yliopisto, 2024-04-12)
Pertussis or whooping cough is a human respiratory tract infection caused by Bordetella pertussis bacteria. Despite extensive vaccinations, pertussis incidence has increased during the last decades. The reasons behind this ...
Androgen receptor therapy resistance in prostate cancer: From the disease model to the mechanisms
(Turun yliopisto, 2024-03-08)
Androgens act through the androgen receptor (AR) and are critical regulators of prostate differentiation and function, as well as prostate cancer (PCa) growth and survival. The development of treatment resistance in ...
Lifestyle habits and novel means for dietary screening and health promotion in pregnant women and children
(Turun yliopisto, 2024-03-01)
Lifestyle habits, including diet and physical activity, that deviate from the recommendations during pregnancy and early childhood may eventually increase the risk for obesity and other lifestyle-related diseases in both ...
Novel bone SPECT-CT methods – Optimization and validation for imaging bone metastases
(Turun yliopisto, 2024-09-27)
Bone single-photon emission computed tomography (SPECT) combined with X-ray computed tomography (SPECT-CT) is expected to replace planar bone scintigraphy (BS) as the routine method for imaging bone metastases. In preparation ...
ERBB4 as a potential therapeutic target in cancer
(Turun yliopisto, 2024-10-04)
ABSTRACT
EGFR/ERBB/HER family of receptor tyrosine kinases are frequently mutated, and hence, aberrantly active in cancer. Currently, numerous ERBB-targeted therapies are used to treat various types of cancer, using ...
The role of HSD17B3 in male development and health: Disruption of testosterone production and its effects
(Turun yliopisto, 2024-10-04)
ABSTRACT
Hydroxysteroid (17β) dehydrogenase type 3 (HSD17B3) is known to be the primary enzyme converting androstenedione (A) to testosterone (T) in human and mouse testes. It is therefore important for male development ...
Surveillance of Antimicrobial Resistant Bacteria in Africa and Namibia
(Turun yliopisto, 2024-09-27)
ABSTRACT
Sub-Saharan Africa faces a growing antimicrobial resistance (AMR) threat. Antimicrobial resistant bacterial organisms pose a serious problem to human infection treatment, particularly urinary tract infections ...