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Ontogeny and function of adipose tissue macrophages
(Turun yliopisto, 2023-11-03)
ABSTRACT
Macrophages are immune cells that also participate in the development and homeostasis of most tissues. Macrophages can originate during embryonic development, first from the yolk sac and later from the fetal ...
CD47 and TREM2 for macrophage-targeted cancer immunotherapy: Antibody validation and ex vivo efficacy in patient-derived explant cultures
(2024-03-13)
Cancer remains a common cause of death worldwide. Cancer cells develop several mechanisms to escape immune destruction, which limits the efficacy of current treatments and creates a need for new therapies. Cancer immunotherapies ...
Characteristics of anti-pertussis toxin antibodies after vaccination and infection
(Turun yliopisto, 2024-04-12)
Pertussis or whooping cough is a human respiratory tract infection caused by Bordetella pertussis bacteria. Despite extensive vaccinations, pertussis incidence has increased during the last decades. The reasons behind this ...
Synnytys- ja lapsivuodeajan infektiot ja niiden mikrobietiologia Varhan alueella vuosina 2013–2022
(2024-03-26)
Lapsivuodeaika tarkoittaa 6–8 synnytyksenjälkeistä viikkoa, jolloin äidin elimistö palaa raskautta edeltäneeseen tilaan. Lapsivuodeajan infektiot ovat merkittävä äidin ja vastasyntyneen sairastavuuden ja kuolleisuuden ...