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Hydroxysteroid (17beta) dehydrogenase 1 expression enhances estrogen action and serves as a potential drug target for reducing estrogen signaling in the uterus and mammary glands
(Turun yliopisto, 2018-01-26)
Hydroxysteroid (17beta) dehydrogenase type 1 (HSD17B1) is a steroidmetabolizing enzyme with a preface for converting the low active estrogen estrone (E1) to highly active estradiol (E2). Accordingly, HSD17B1 is expressed ...