Good long-term results of sacral neuromodulation for endometriosis related chronic pelvic pain

dc.contributor.authorZegrea, Adrian
dc.contributor.authorOjala, Emilia
dc.contributor.authorKirss, Jaan
dc.contributor.authorSuvitie, Pia
dc.contributor.authorVarpe, Pirita
dc.contributor.authorMakela-Kaikkonen, Johanna
dc.contributor.authorRautio, Tero
dc.contributor.authorSeikkula, Jaana
dc.contributor.authorUkkonen, Mika
dc.contributor.authorLavonius, Maija
dc.contributor.authorPinta, Tarja
dc.contributor.organizationfi=kirurgia|en=Surgery|
dc.contributor.organizationfi=kliininen laitos|en=Department of Clinical Medicine|
dc.contributor.organizationfi=synnytys- ja naistentautioppi|en=Obstetrics and Gynaecology|
dc.contributor.organizationfi=tyks, vsshp|en=tyks, varha|
dc.contributor.organization-code1.2.246.10.2458963.20.74725736230
dc.contributor.organization-code1.2.246.10.2458963.20.97295082107
dc.contributor.organization-code2607300
dc.contributor.organization-code2607309
dc.converis.publication-id491891199
dc.converis.urlhttps://research.utu.fi/converis/portal/Publication/491891199
dc.date.accessioned2025-08-28T01:08:12Z
dc.date.available2025-08-28T01:08:12Z
dc.description.abstract<p><strong>Background: </strong>Sacral neuromodulation (SNM) is an established therapy in urology and gastroenterological surgery for treatment of overactive bladder symptoms, urge urinary incontinence or fecal incontinence. SNM has also been used with good results in patients with chronic pelvic pain (CPP). Our aim was to analyze long-term results of SNM in Finnish patients with endometriosis related CPP.</p><p><strong>Methods: </strong>This is a register-based retrospective study including all the endometriosis patients treated with SNM for CPP in Finland between 2004 and 2017. There were four centers where these procedures were performed, two University Hospitals and two Central Hospitals. Long-term results were assessed by phone interview in spring 2021.</p><p><strong>Results: </strong>A total of 16 women with endometriosis, with a median age of 39 (25-50) years, underwent SNM treatment for chronic pelvic pain (CPP), with the median follow-up time of 73 (48-85) months. The Implantable Pulse Generator (IPG) was implanted to 14 patients (88%). By the end of the follow-up period, 10 patients (62,5% of all patients and 71% of those who received IPG) had a functional SNM. Pain was assessed by numeral rating scale (NRS) and decreased from a median of 7.4 (3.6-10) to 2.3 (0-6.5).</p><p><strong>Conclusions: </strong>SNM could be a good option in the treatment of endometriosis related chronic pelvic pain when standard therapy is not enough.</p>
dc.identifier.eissn1472-6874
dc.identifier.jour-issn1472-6874
dc.identifier.olddbid207080
dc.identifier.oldhandle10024/190107
dc.identifier.urihttps://www.utupub.fi/handle/11111/50322
dc.identifier.urlhttps://doi.org/10.1186/s12905-025-03699-y
dc.identifier.urnURN:NBN:fi-fe2025082791501
dc.language.isoen
dc.okm.affiliatedauthorOjala, Emilia
dc.okm.affiliatedauthorSuvitie, Pia
dc.okm.affiliatedauthorVarpe, Pirita
dc.okm.affiliatedauthorLavonius, Maija
dc.okm.affiliatedauthorDataimport, tyks, vsshp
dc.okm.discipline3123 Gynaecology and paediatricsen_GB
dc.okm.discipline3126 Surgery, anesthesiology, intensive care, radiologyen_GB
dc.okm.discipline3123 Naisten- ja lastentauditfi_FI
dc.okm.discipline3126 Kirurgia, anestesiologia, tehohoito, radiologiafi_FI
dc.okm.internationalcopublicationinternational co-publication
dc.okm.internationalityInternational publication
dc.okm.typeA1 ScientificArticle
dc.publisherSpringer Science and Business Media LLC
dc.publisher.countryUnited Kingdomen_GB
dc.publisher.countryBritanniafi_FI
dc.publisher.country-codeGB
dc.publisher.placeLONDON
dc.relation.articlenumber162
dc.relation.doi10.1186/s12905-025-03699-y
dc.relation.ispartofjournalBMC Women's Health
dc.relation.issue1
dc.relation.volume25
dc.source.identifierhttps://www.utupub.fi/handle/10024/190107
dc.titleGood long-term results of sacral neuromodulation for endometriosis related chronic pelvic pain
dc.year.issued2025

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