Optimising the antibiotic treatment of uncomplicated acute appendicitis: a protocol for a multicentre randomised clinical trial (APPAC II trial)

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dc.contributor.authorHaijanen J
dc.contributor.authorSippola S
dc.contributor.authorGrönroos J
dc.contributor.authorRautio T
dc.contributor.authorNordström P
dc.contributor.authorRantanen T
dc.contributor.authorAarnio M
dc.contributor.authorIlves I
dc.contributor.authorHurme S
dc.contributor.authorMarttila H
dc.contributor.authorVirtanen J
dc.contributor.authorMattila A
dc.contributor.authorPaajanen H
dc.contributor.authorSalminen P
dc.contributor.authorand on behalf of the APPAC study group
dc.contributor.organizationfi=biostatistiikka|en=Biostatistics|
dc.contributor.organizationfi=infektiotautioppi|en=Infectious Diseases|
dc.contributor.organizationfi=kirurgia|en=Surgery|
dc.contributor.organizationfi=kuvantaminen ja kliininen diagnostiikka|en=Imaging and Clinical Diagnostics|
dc.contributor.organizationfi=tyks, vsshp|en=tyks, varha|
dc.contributor.organization-code1.2.246.10.2458963.20.69079168212
dc.contributor.organization-code1.2.246.10.2458963.20.89365200099
dc.contributor.organization-code1.2.246.10.2458963.20.97295082107
dc.contributor.organization-code2607306
dc.converis.publication-id38132282
dc.converis.urlhttps://research.utu.fi/converis/portal/Publication/38132282
dc.date.accessioned2022-10-28T13:49:47Z
dc.date.available2022-10-28T13:49:47Z
dc.description.abstract<h3>Discussion</h3><p>To our knowledge, APPAC II trial is the first randomised controlled trial comparing per oral antibiotic monotherapy with intravenous antibiotic therapy continued by per oral antibiotics in the treatment of uncomplicated acute appendicitis. The APPAC II trial aims to add clinical evidence on the debated role of antibiotics as the first-line treatment for a CT-confirmed uncomplicated acute appendicitis as well as to optimise the non-operative treatment for uncomplicated acute appendicitis.</p>
dc.identifier.jour-issn1471-2482
dc.identifier.olddbid184592
dc.identifier.oldhandle10024/167686
dc.identifier.urihttps://www.utupub.fi/handle/11111/38673
dc.identifier.urnURN:NBN:fi-fe2021042823744
dc.language.isoen
dc.okm.affiliatedauthorHaijanen, Jussi
dc.okm.affiliatedauthorSippola, Suvi
dc.okm.affiliatedauthorGrönroos, Juha
dc.okm.affiliatedauthorHurme, Saija
dc.okm.affiliatedauthorMarttila, Harri
dc.okm.affiliatedauthorKallio, Johanna
dc.okm.affiliatedauthorSalminen, Paulina
dc.okm.affiliatedauthorDataimport, tyks, vsshp
dc.okm.discipline3126 Surgery, anesthesiology, intensive care, radiologyen_GB
dc.okm.discipline3126 Kirurgia, anestesiologia, tehohoito, radiologiafi_FI
dc.okm.internationalcopublicationnot an international co-publication
dc.okm.internationalityInternational publication
dc.okm.typeA1 ScientificArticle
dc.relation.articlenumber117
dc.relation.doi10.1186/s12893-018-0451-y
dc.relation.ispartofjournalBMC Surgery
dc.relation.volume18
dc.source.identifierhttps://www.utupub.fi/handle/10024/167686
dc.titleOptimising the antibiotic treatment of uncomplicated acute appendicitis: a protocol for a multicentre randomised clinical trial (APPAC II trial)
dc.year.issued2018

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