Synthesis of fully protected trinucleotide building blocks on a disulphide-linked soluble support
ROYAL SOC CHEMISTRY
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Tiivistelmä
In recent years, preparation of fully protected trinucleotide phosphoramidites as synthons for the codon-based synthesis of gene libraries as well as for the assembly of oligonucleotides from blockmers has gained much attention. We here describe the preparation of such trinucleotide synthons on a soluble support using a disulphide linker.