Generation of two human induced pluripotent stem cell lines from peripheral blood mononuclear cells featuring normal or mutated STAB1 gene

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dc.contributor.authorSandelin, Sanne
dc.contributor.authorGiannareas, Nikolaos
dc.contributor.authorKere, Juha
dc.contributor.authorSeppänen, Mikko R. J.
dc.contributor.authorHollmen, Maija
dc.contributor.authorNärvä, Elisa
dc.contributor.organizationfi=MediCity|en=MediCity|
dc.contributor.organizationfi=biolääketieteen laitos|en=Institute of Biomedicine|
dc.contributor.organizationfi=tyks, vsshp|en=tyks, varha|
dc.contributor.organization-code1.2.246.10.2458963.20.77952289591
dc.contributor.organization-code1.2.246.10.2458963.20.83772236069
dc.converis.publication-id498990284
dc.converis.urlhttps://research.utu.fi/converis/portal/Publication/498990284
dc.date.accessioned2026-01-21T13:39:43Z
dc.date.available2026-01-21T13:39:43Z
dc.description.abstract<p>Here, we report the establishment of a human induced pluripotent stem cell (hiPSC) line TUR-STAB1-B1 derived from peripheral blood mononuclear cells of a patient carrying heterozygous mutations 52,509,890 C>A 790L>I and 52,520,515 G>A 1872R>H on STAB1 gene in addition to a normal control cell line TUR-B1. The pluripotency, identity, quality, safety, and sequence of the mutation sites of the cell lines were confirmed. The generated patient-specific cell line will facilitate detailed studies of the STAB1 in various differentiated cell types.</p>
dc.identifier.eissn1876-7753
dc.identifier.jour-issn1873-5061
dc.identifier.olddbid213222
dc.identifier.oldhandle10024/196240
dc.identifier.urihttps://www.utupub.fi/handle/11111/54930
dc.identifier.urlhttps://doi.org/10.1016/j.scr.2025.103750
dc.identifier.urnURN:NBN:fi-fe2025082792830
dc.language.isoen
dc.okm.affiliatedauthorSandelin, Sanne
dc.okm.affiliatedauthorGiannareas, Nikolaos
dc.okm.affiliatedauthorHollmen, Maija
dc.okm.affiliatedauthorNärvä, Elisa
dc.okm.affiliatedauthorDataimport, tyks, vsshp
dc.okm.discipline3111 Biomedicineen_GB
dc.okm.discipline3111 Biolääketieteetfi_FI
dc.okm.internationalcopublicationinternational co-publication
dc.okm.internationalityInternational publication
dc.okm.typeA1 ScientificArticle
dc.publisherElsevier
dc.publisher.countryNetherlandsen_GB
dc.publisher.countryAlankomaatfi_FI
dc.publisher.country-codeNL
dc.publisher.placeAMSTERDAM
dc.relation.articlenumber103750
dc.relation.doi10.1016/j.scr.2025.103750
dc.relation.ispartofjournalStem Cell Research
dc.relation.volume87
dc.source.identifierhttps://www.utupub.fi/handle/10024/196240
dc.titleGeneration of two human induced pluripotent stem cell lines from peripheral blood mononuclear cells featuring normal or mutated STAB1 gene
dc.year.issued2025

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