Close-loop dynamic nanohybrids on collagen-ark with in situ gelling transformation capability for biomimetic stage-specific diabetic wound healing

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dc.contributor.authorZehua Liu
dc.contributor.authorYunzhan Li
dc.contributor.authorWei Li
dc.contributor.authorWenhua Lian
dc.contributor.authorMarianna Kemell
dc.contributor.authorSami Hietala
dc.contributor.authorPatrícia Figueiredo
dc.contributor.authorLi Li
dc.contributor.authorErmei Mäkilä
dc.contributor.authorMing Ma
dc.contributor.authorJarno Salonen
dc.contributor.authorJouni T. Hirvonen
dc.contributor.authorDongfei Liu
dc.contributor.authorHongbo Zhang
dc.contributor.authorXianming Deng
dc.contributor.authorHélder A. Santos
dc.contributor.organizationfi=Turun biotiedekeskus|en=Turku Bioscience Centre|
dc.contributor.organizationfi=teollisuusfysiikan laboratorio|en=Laboratory of Industrial Physics|
dc.contributor.organization-code1.2.246.10.2458963.20.18586209670
dc.contributor.organization-code1.2.246.10.2458963.20.66904373678
dc.converis.publication-id39807705
dc.converis.urlhttps://research.utu.fi/converis/portal/Publication/39807705
dc.date.accessioned2022-10-28T14:11:58Z
dc.date.available2022-10-28T14:11:58Z
dc.description.abstractHere, an oxidation/acid dual-responsive nanohybrids/ark system was produced. The microfluidics-produced nanohybrids endow the system with an orchestrated cascade from wound detection, reactive oxygen species scavenging, drug release to hydrogel formation. The drug release behavior imitates the dynamic wound healing process, thus rendering an enhanced bio-mimetic regeneration.
dc.format.pagerange385
dc.format.pagerange393
dc.identifier.jour-issn2051-6347
dc.identifier.olddbid186854
dc.identifier.oldhandle10024/169948
dc.identifier.urihttps://www.utupub.fi/handle/11111/40492
dc.identifier.urlhttps://pubs.rsc.org/en/Content/ArticleLanding/2019/MH/C8MH01145A#!divAbstract
dc.identifier.urnURN:NBN:fi-fe2021042825528
dc.language.isoen
dc.okm.affiliatedauthorMäkilä, Ermei
dc.okm.affiliatedauthorSalonen, Jarno
dc.okm.affiliatedauthorZhang, Hongbo
dc.okm.discipline116 Chemical sciencesen_GB
dc.okm.discipline1182 Biochemistry, cell and molecular biologyen_GB
dc.okm.discipline116 Kemiafi_FI
dc.okm.discipline1182 Biokemia, solu- ja molekyylibiologiafi_FI
dc.okm.internationalcopublicationinternational co-publication
dc.okm.internationalityInternational publication
dc.okm.typeA1 ScientificArticle
dc.publisherROYAL SOC CHEMISTRY
dc.publisher.countryUnited Kingdomen_GB
dc.publisher.countryBritanniafi_FI
dc.publisher.country-codeGB
dc.relation.doi10.1039/c8mh01145a
dc.relation.ispartofjournalMaterials Horizons
dc.relation.issue2
dc.relation.volume6
dc.source.identifierhttps://www.utupub.fi/handle/10024/169948
dc.titleClose-loop dynamic nanohybrids on collagen-ark with in situ gelling transformation capability for biomimetic stage-specific diabetic wound healing
dc.year.issued2019

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