Identification of Non-HLA Genes Associated with Celiac Disease and Country-Specific Differences in a Large, International Pediatric Cohort

Tietueen suppeat tiedot
dc.contributor.authorSharma A
dc.contributor.authorLiu X
dc.contributor.authorHadley D
dc.contributor.authorHagopian W
dc.contributor.authorLiu E
dc.contributor.authorChen WM
dc.contributor.authorOnengut-Gumuscu S
dc.contributor.authorSimell V
dc.contributor.authorRewers M
dc.contributor.authorZiegler AG
dc.contributor.authorLernmarklo A
dc.contributor.authorSimell O
dc.contributor.authorToppari J
dc.contributor.authorKrischer JP
dc.contributor.authorAkolkar B
dc.contributor.authorRich SS
dc.contributor.authorAgardh D
dc.contributor.authorShe JX
dc.contributor.authorTeddy Study group
dc.contributor.organizationfi=fysiologia|en=Physiology|
dc.contributor.organizationfi=lastentautioppi|en=Paediatrics and Adolescent Medicine|
dc.contributor.organizationfi=lääketieteen mikrobiologia ja immunologia|en=Medical Microbiology and Immunology|
dc.contributor.organizationfi=tyks, vsshp|en=tyks, varha|
dc.contributor.organization-code1.2.246.10.2458963.20.16325436125
dc.contributor.organization-code1.2.246.10.2458963.20.77381963311
dc.contributor.organization-code2607103
dc.contributor.organization-code2607313
dc.converis.publication-id2680954
dc.converis.urlhttps://research.utu.fi/converis/portal/Publication/2680954
dc.date.accessioned2022-10-28T14:08:41Z
dc.date.available2022-10-28T14:08:41Z
dc.description.abstract<p> In conclusion, using a genetic analysis of a large international cohort of children, we associated celiac disease development with 5 non-HLA regions previously associated with the disease and 8 regions not previously associated with celiac disease. We identified 5 regions associated with development of tTGA. Two loci associated with celiac disease progression reached a genome-wide association threshold in subjects from Sweden.</p>
dc.identifier.jour-issn1932-6203
dc.identifier.olddbid186530
dc.identifier.oldhandle10024/169624
dc.identifier.urihttps://www.utupub.fi/handle/11111/38733
dc.identifier.urnURN:NBN:fi-fe2021042714787
dc.language.isoen
dc.okm.affiliatedauthorSimell, Ville
dc.okm.affiliatedauthorSimell, Olli
dc.okm.affiliatedauthorToppari, Jorma
dc.okm.affiliatedauthorAdamsson, Annika
dc.okm.affiliatedauthorIlonen, Jorma
dc.okm.affiliatedauthorKoivu, Annika
dc.okm.affiliatedauthorMäntymäki, Elina
dc.okm.affiliatedauthorMykkänen, Juha
dc.okm.affiliatedauthorRajala, Petra
dc.okm.affiliatedauthorRomo, Minna
dc.okm.affiliatedauthorSimell, Satu
dc.okm.affiliatedauthorSimell, Tuula
dc.okm.affiliatedauthorSjöberg, Maija
dc.okm.affiliatedauthorVarjonen, Eeva-Liisa
dc.okm.affiliatedauthorDataimport, tyks, vsshp
dc.okm.discipline3123 Gynaecology and paediatricsen_GB
dc.okm.discipline3123 Naisten- ja lastentauditfi_FI
dc.okm.internationalcopublicationinternational co-publication
dc.okm.internationalityInternational publication
dc.okm.typeA1 ScientificArticle
dc.publisherPUBLIC LIBRARY SCIENCE
dc.relation.articlenumberARTN e0152476
dc.relation.doi10.1371/journal.pone.0152476
dc.relation.ispartofjournalPLoS ONE
dc.relation.issue3
dc.relation.volume11
dc.source.identifierhttps://www.utupub.fi/handle/10024/169624
dc.titleIdentification of Non-HLA Genes Associated with Celiac Disease and Country-Specific Differences in a Large, International Pediatric Cohort
dc.year.issued2016

Tiedostot

Näytetään 1 - 1 / 1
Name:
asset.pdf
Size:
3.78 MB
Format:
Adobe Portable Document Format
Lataa

Kokoelmat

Rinnakkaistallenteet