68Ga-DOTA-E[c(RGDfK)]2 Positron Emission Tomography Imaging of SHARPIN-Regulated Integrin Activity in Mice

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dc.contributor.authorRiikka Siitonen
dc.contributor.authorEmilia Peuhu
dc.contributor.authorAnu K Autio
dc.contributor.authorHeidi Liljenbäck
dc.contributor.authorElina Mattila
dc.contributor.authorOlli Metsälä
dc.contributor.authorMeeri Käkelä
dc.contributor.authorTiina Saanijoki
dc.contributor.authorIngrid Dijkgraaf
dc.contributor.authorSirpa Jalkanen
dc.contributor.authorJohanna Ivaska
dc.contributor.authorAnne Roivainen
dc.contributor.organizationfi=MediCity|en=MediCity|
dc.contributor.organizationfi=PET-keskus|en=Turku PET Centre|
dc.contributor.organizationfi=Turun biotiedekeskus|en=Turku Bioscience Centre|
dc.contributor.organizationfi=biolääketieteen laitos|en=Institute of Biomedicine|
dc.contributor.organizationfi=tyks, vsshp|en=tyks, varha|
dc.contributor.organization-code1.2.246.10.2458963.20.14646305228
dc.contributor.organization-code1.2.246.10.2458963.20.18586209670
dc.contributor.organization-code1.2.246.10.2458963.20.77952289591
dc.contributor.organization-code2609810
dc.converis.publication-id41392288
dc.converis.urlhttps://research.utu.fi/converis/portal/Publication/41392288
dc.date.accessioned2025-08-28T00:41:53Z
dc.date.available2025-08-28T00:41:53Z
dc.description.abstractSharpincpdm mice demonstrated increased integrin activity and vascularization in B16-F10-luc melanoma tumors, as demonstrated by RGD-based in vivo PET imaging. These data indicate that SHARPIN, a protein previously associated with increased cancer growth and metastasis, may also have important regulatory roles in controlling the tumor microenvironment.
dc.format.pagerange1380
dc.format.pagerange1387
dc.identifier.eissn1535-5667
dc.identifier.jour-issn0161-5505
dc.identifier.olddbid206226
dc.identifier.oldhandle10024/189253
dc.identifier.urihttps://www.utupub.fi/handle/11111/44607
dc.identifier.urnURN:NBN:fi-fe2021042713122
dc.language.isoen
dc.okm.affiliatedauthorViitanen, Riikka
dc.okm.affiliatedauthorPeuhu, Emilia
dc.okm.affiliatedauthorAutio, Anu
dc.okm.affiliatedauthorLiljenbäck, Heidi
dc.okm.affiliatedauthorMetsälä, Olli
dc.okm.affiliatedauthorKäkelä, Meeri
dc.okm.affiliatedauthorSaanijoki, Tiina
dc.okm.affiliatedauthorJalkanen, Sirpa
dc.okm.affiliatedauthorIvaska, Johanna
dc.okm.affiliatedauthorRoivainen, Anne
dc.okm.affiliatedauthorDataimport, MediCity
dc.okm.affiliatedauthorDataimport, tyks, vsshp
dc.okm.discipline1182 Biochemistry, cell and molecular biologyen_GB
dc.okm.discipline1182 Biokemia, solu- ja molekyylibiologiafi_FI
dc.okm.internationalcopublicationinternational co-publication
dc.okm.internationalityInternational publication
dc.okm.typeA1 ScientificArticle
dc.publisher.countryUnited Statesen_GB
dc.publisher.countryYhdysvallat (USA)fi_FI
dc.publisher.country-codeUS
dc.relation.doi10.2967/jnumed.118.222026
dc.relation.ispartofjournalJournal of Nuclear Medicine
dc.relation.issue10
dc.relation.volume60
dc.source.identifierhttps://www.utupub.fi/handle/10024/189253
dc.title68Ga-DOTA-E[c(RGDfK)]2 Positron Emission Tomography Imaging of SHARPIN-Regulated Integrin Activity in Mice
dc.year.issued2019

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