Platelet-rich plasma does not influence magnetic resonance imaging findings of the gluteus muscles after total hip arthroplasty through the Hardinge approach

dc.contributor.authorNieminen, Anette
dc.contributor.authorNurminen, Janne
dc.contributor.authorAavikko, Anni
dc.contributor.authorPuhakka, Jani
dc.contributor.authorHaapala, Jussi
dc.contributor.authorKeemu, Hannes
dc.contributor.authorKukkonen, Juha
dc.contributor.authorAlho, Ari
dc.contributor.authorUusalo, Panu
dc.contributor.authorMakela, Keijo
dc.contributor.authorKosola, Jussi
dc.contributor.organizationfi=anestesiologia ja tehohoito|en=Anaesthesiology, Intensive Care|
dc.contributor.organizationfi=kuvantaminen ja kliininen diagnostiikka|en=Imaging and Clinical Diagnostics|
dc.contributor.organizationfi=ortopedia ja traumatologia|en=Orthopaedics and Traumatology|
dc.contributor.organizationfi=tyks, vsshp|en=tyks, varha|
dc.contributor.organization-code1.2.246.10.2458963.20.82197219338
dc.contributor.organization-code1.2.246.10.2458963.20.90281651480
dc.contributor.organization-code2607303
dc.converis.publication-id485058241
dc.converis.urlhttps://research.utu.fi/converis/portal/Publication/485058241
dc.date.accessioned2025-08-27T23:42:39Z
dc.date.available2025-08-27T23:42:39Z
dc.description.abstract<p><b>Objective</b></p><p>Total hip arthroplasty through the Hardinge approach damages the hip abductor muscles. MRI can be used to assess adverse postoperative events. In this prospective randomized controlled trial, we evaluated MRI findings and whether platelet-rich plasma affected postoperative healing of the gluteal muscles (gluteus medius and minimus).<br></p><p><b>Materials and methods</b><br></p><p>Forty patients with hip osteoarthritis requiring treatment with total hip arthroplasty, aged between 60 and 76 years, were included. Patients were randomized into two groups: 19 patients in the platelet-rich plasma group and 21 in the placebo group. Platelet-rich plasma or placebo was injected into the gluteus medius tendon incision line during closure. Postoperative hip MRI and plain radiographs were taken 3 and 12 months after surgery.<br></p><p><b>Results</b><br></p><p>MRI showed fatty atrophy of the gluteal muscles in all 40 patients (100%), gluteal muscle tear in 11 patients (28%), and atrophy in 16 patients (40%) at both 3 and 12 months postoperatively. Fluid collections related to the operated hip joint were seen in 18 patients (45%) at 3 months and 13 patients (33%) at 12 months, heterotopic ossification formation in nine patients (23%) at 3 months, and 12 patients (31%) at 12 months. There were no significant differences in imaging findings between the two groups.<br></p><p><b>Conclusion</b><br></p><p>MRI can be a valuable tool for evaluating postoperative healing after total hip arthroplasty. Fatty atrophy of the gluteal muscles was a common finding. Platelet-rich plasma injection into the gluteus medius tendon did not improve healing detected by MRI.</p>
dc.identifier.eissn1432-2161
dc.identifier.jour-issn0364-2348
dc.identifier.olddbid204467
dc.identifier.oldhandle10024/187494
dc.identifier.urihttps://www.utupub.fi/handle/11111/52741
dc.identifier.urlhttps://doi.org/10.1007/s00256-025-04876-8
dc.identifier.urnURN:NBN:fi-fe2025082790450
dc.language.isoen
dc.okm.affiliatedauthorHeiskanen, Anette
dc.okm.affiliatedauthorNurminen, Janne
dc.okm.affiliatedauthorKeemu, Hannes
dc.okm.affiliatedauthorUusalo, Panu
dc.okm.affiliatedauthorMäkelä, Keijo
dc.okm.affiliatedauthorDataimport, tyks, vsshp
dc.okm.discipline3126 Surgery, anesthesiology, intensive care, radiologyen_GB
dc.okm.discipline3126 Kirurgia, anestesiologia, tehohoito, radiologiafi_FI
dc.okm.internationalcopublicationnot an international co-publication
dc.okm.internationalityInternational publication
dc.okm.typeA1 ScientificArticle
dc.publisherSPRINGER
dc.publisher.countryGermanyen_GB
dc.publisher.countrySaksafi_FI
dc.publisher.country-codeDE
dc.publisher.placeNEW YORK
dc.relation.doi10.1007/s00256-025-04876-8
dc.relation.ispartofjournalSkeletal Radiology
dc.source.identifierhttps://www.utupub.fi/handle/10024/187494
dc.titlePlatelet-rich plasma does not influence magnetic resonance imaging findings of the gluteus muscles after total hip arthroplasty through the Hardinge approach
dc.year.issued2025

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