Macrolide-resistant Bordetella pertussis strain identified during an ongoing epidemic, Finland, January to October 2024

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dc.contributor.authorMiettinen, Milja
dc.contributor.authorBarkoff, Alex-Mikael
dc.contributor.authorNyqvist, Aino
dc.contributor.authorSavolainen-Kopra, Carita
dc.contributor.authorAntikainen, Jenni
dc.contributor.authorMertsola, Jussi
dc.contributor.authorIvaska, Lauri
dc.contributor.authorHe, Qiushui
dc.contributor.organizationfi=InFLAMES Lippulaiva|en=InFLAMES Flagship|
dc.contributor.organizationfi=biolääketieteen laitos|en=Institute of Biomedicine|
dc.contributor.organizationfi=lastenpsykiatrian tutkimuskeskus|en=Research Centre for Child Psychiatry|
dc.contributor.organizationfi=lastentautioppi|en=Paediatrics and Adolescent Medicine|
dc.contributor.organizationfi=tyks, vsshp|en=tyks, varha|
dc.contributor.organization-code1.2.246.10.2458963.20.40612039509
dc.contributor.organization-code1.2.246.10.2458963.20.68445910604
dc.contributor.organization-code1.2.246.10.2458963.20.77952289591
dc.contributor.organization-code1.2.246.10.2458963.20.83706093164
dc.converis.publication-id477189947
dc.converis.urlhttps://research.utu.fi/converis/portal/Publication/477189947
dc.date.accessioned2025-08-27T23:17:17Z
dc.date.available2025-08-27T23:17:17Z
dc.description.abstractSince April 2024, a pertussis epidemic has been ongoing in Finland with 2,215 notified cases by end October. Of them, 30.1% (n = 667) were aged 10-14 years. Of the 462 <i>Bordetella pertussis</i> isolates characterised, one was macrolide-resistant (minimum inhibitory concentration (MIC) of erythromycin, azithromycin and clarithromycin > 256 μg/mL). The resistant isolate was serotype FIM2, vaccine antigen pertactin-deficient and harboured <i>ptxP3</i> allele. The emergence of macrolide-resistant <i>B. pertussis</i> in Europe is worrisome and its rapid identification is important.
dc.identifier.eissn1560-7917
dc.identifier.jour-issn1025-496X
dc.identifier.olddbid203733
dc.identifier.oldhandle10024/186760
dc.identifier.urihttps://www.utupub.fi/handle/11111/47037
dc.identifier.urlhttps://doi.org/10.2807/1560-7917.es.2024.29.49.2400765
dc.identifier.urnURN:NBN:fi-fe2025082790208
dc.language.isoen
dc.okm.affiliatedauthorMiettinen, Milja
dc.okm.affiliatedauthorBarkoff, Alex-Mikael
dc.okm.affiliatedauthorMertsola, Jussi
dc.okm.affiliatedauthorIvaska, Lauri
dc.okm.affiliatedauthorHe, Qiushui
dc.okm.affiliatedauthorDataimport, tyks, vsshp
dc.okm.discipline3111 Biomedicineen_GB
dc.okm.discipline3111 Biolääketieteetfi_FI
dc.okm.internationalcopublicationnot an international co-publication
dc.okm.internationalityInternational publication
dc.okm.typeA1 ScientificArticle
dc.publisherEuropean Centre for Disease Control and Prevention (ECDC)
dc.publisher.countrySwedenen_GB
dc.publisher.countryRuotsifi_FI
dc.publisher.country-codeSE
dc.relation.doi10.2807/1560-7917.ES.2024.29.49.2400765
dc.relation.ispartofjournalEurosurveillance
dc.relation.issue49
dc.relation.volume29
dc.source.identifierhttps://www.utupub.fi/handle/10024/186760
dc.titleMacrolide-resistant Bordetella pertussis strain identified during an ongoing epidemic, Finland, January to October 2024
dc.year.issued2024

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