Absence from work in the 12 months following mild traumatic brain injury in Europe: a CENTER-TBI cohort study

dc.contributor.authorJacob, Louis
dc.contributor.authorCastro, John
dc.contributor.authorHeslot, Camille
dc.contributor.authorAndelic, Nada
dc.contributor.authorTenovuo, Olli
dc.contributor.authorCENTER-TBI Participants and Investigators (Appendix)
dc.contributor.authorAzouvi, Philippe
dc.contributor.organizationfi=kliiniset neurotieteet|en=Clinical Neurosciences|
dc.contributor.organizationfi=tyks, vsshp|en=tyks, varha|
dc.contributor.organization-code1.2.246.10.2458963.20.74845969893
dc.converis.publication-id504660679
dc.converis.urlhttps://research.utu.fi/converis/portal/Publication/504660679
dc.date.accessioned2026-01-21T12:30:09Z
dc.date.available2026-01-21T12:30:09Z
dc.description.abstract<h3>Background</h3><p>Most of the prior research on absence from work after a mild traumatic brain injury (mTBI) was of a small sample size and had a limited number of follow-up assessments.</p><h3>Objectives</h3><p>Therefore, this study investigated the prevalence of absence from work, trajectories, and associated factors in the 12 months following mTBI in Europe.</p><h3>Methods</h3><p>Data from a European cohort (CENTER-TBI) were used. Absence from work was assessed at 2 weeks, 3 months, 6 months, and 12 months after mTBI. Associated factors included sociodemographic factors, current psychoactive substance use, pre-injury medical history, injury-related factors, medical care, complications, and discharge, and 2-week follow-up questionnaires. Inferential analyses relied on generalized estimating equations.</p><h3>Results</h3><p>This study included 1080 adults with mTBI who were working at the time of the injury (median [IQR] age, 46.0 [23.0] years; 69 % men). Absence from work decreased from 32 % at 2 weeks to 20 % at 12 months after the injury (<em>P</em> < 0.001). Around 76 % of adults returned to work within the first 3 months, whereas > 43 % of those absent from work at 3 months remained absent at 12 months. The 3 factors with the strongest association with absence from work were admission to hospital wards (OR = 2.57) or intensive care units (OR = 4.76), the presence of a pre-injury psychiatric disorder (OR = 2.55), and older age (OR = 1.61).</p><h3>Conclusions</h3><p>One-fifth of workers with mTBI were absent from work 12 months after the injury. Early identification of those at particular risk for not returning to work should be a clinical priority.</p>
dc.identifier.eissn1877-0665
dc.identifier.jour-issn1877-0657
dc.identifier.olddbid212579
dc.identifier.oldhandle10024/195597
dc.identifier.urihttps://www.utupub.fi/handle/11111/52758
dc.identifier.urlhttps://doi.org/10.1016/j.rehab.2025.102017
dc.identifier.urnURN:NBN:fi-fe202601215909
dc.language.isoen
dc.okm.affiliatedauthorTenovuo, Olli
dc.okm.affiliatedauthorDataimport, tyks, vsshp
dc.okm.discipline3112 Neurosciencesen_GB
dc.okm.discipline3112 Neurotieteetfi_FI
dc.okm.internationalcopublicationinternational co-publication
dc.okm.internationalityInternational publication
dc.okm.typeA1 ScientificArticle
dc.publisherElsevier Masson
dc.publisher.countryFranceen_GB
dc.publisher.countryRanskafi_FI
dc.publisher.country-codeFR
dc.relation.articlenumber102017
dc.relation.doi10.1016/j.rehab.2025.102017
dc.relation.ispartofjournalAnnals of physical and rehabilitation medicine
dc.relation.issue8
dc.relation.volume68
dc.source.identifierhttps://www.utupub.fi/handle/10024/195597
dc.titleAbsence from work in the 12 months following mild traumatic brain injury in Europe: a CENTER-TBI cohort study
dc.year.issued2025

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