Adaptation of bacteria to glyphosate: a microevolutionary perspective of the enzyme 5-enolpyruvylshikimate-3-phosphate synthase

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dc.contributor.authorRainio Miia J
dc.contributor.authorRuuskanen Suvi
dc.contributor.authorHelander Marjo
dc.contributor.authorSaikkonen Kari
dc.contributor.authorSaloniemi Irma
dc.contributor.authorPuigbò Pere
dc.contributor.organizationfi=ekologia ja evoluutiobiologia|en=Ecology and Evolutionary Biology |
dc.contributor.organization-code1.2.246.10.2458963.20.20415010352
dc.converis.publication-id53327474
dc.converis.urlhttps://research.utu.fi/converis/portal/Publication/53327474
dc.date.accessioned2025-08-28T01:26:46Z
dc.date.available2025-08-28T01:26:46Z
dc.description.abstractGlyphosate is the leading herbicide worldwide, but it also affects prokaryotes because it targets the central enzyme (5-enolpyruvylshikimate-3-phosphate, EPSP) of the shikimate pathway in the synthesis of the three essential aromatic amino acids in bacteria, fungi and plants. Our results reveal that bacteria may easily become resistant to glyphosate through changes in the 5-enolpyruvylshikimate-3-phosphate synthase active site. This indicates the importance of examining how glyphosate affects microbe-mediated ecosystem functions and human microbiomes.
dc.identifier.eissn1758-2229
dc.identifier.jour-issn1758-2229
dc.identifier.olddbid207558
dc.identifier.oldhandle10024/190585
dc.identifier.urihttps://www.utupub.fi/handle/11111/52727
dc.identifier.urnURN:NBN:fi-fe2021042826711
dc.language.isoen
dc.okm.affiliatedauthorRainio, Miia
dc.okm.affiliatedauthorRuuskanen, Suvi
dc.okm.affiliatedauthorHelander, Marjo
dc.okm.affiliatedauthorSaikkonen, Kari
dc.okm.affiliatedauthorSaloniemi, Irma
dc.okm.affiliatedauthorPuigbo, Pedro
dc.okm.discipline1181 Ecology, evolutionary biologyen_GB
dc.okm.internationalcopublicationinternational co-publication
dc.okm.internationalityInternational publication
dc.okm.typeA1 ScientificArticle
dc.publisherWILEY
dc.publisher.countryUnited Statesen_GB
dc.publisher.countryYhdysvallat (USA)fi_FI
dc.publisher.country-codeUS
dc.relation.doi10.1111/1758-2229.12931
dc.relation.ispartofjournalEnvironmental Microbiology Reports
dc.source.identifierhttps://www.utupub.fi/handle/10024/190585
dc.titleAdaptation of bacteria to glyphosate: a microevolutionary perspective of the enzyme 5-enolpyruvylshikimate-3-phosphate synthase
dc.year.issued2021

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