Finnish children carrying the high-risk HLA genotype have a 45-fold increased risk of type 1 diabetes compared to peers with neutral or protective genotypes
| dc.contributor.author | Taka Antti-Mathias | |
| dc.contributor.author | But Anna | |
| dc.contributor.author | Lempainen Johanna | |
| dc.contributor.author | Vatanen Tommi | |
| dc.contributor.author | Härkönen Taina | |
| dc.contributor.author | Ilonen Jorma | |
| dc.contributor.author | Knip Mikael | |
| dc.contributor.organization | fi=biolääketieteen laitos|en=Institute of Biomedicine| | |
| dc.contributor.organization | fi=lastentautioppi|en=Paediatrics and Adolescent Medicine| | |
| dc.contributor.organization | fi=tyks, vsshp|en=tyks, varha| | |
| dc.contributor.organization-code | 1.2.246.10.2458963.20.40612039509 | |
| dc.contributor.organization-code | 1.2.246.10.2458963.20.77952289591 | |
| dc.converis.publication-id | 179032396 | |
| dc.converis.url | https://research.utu.fi/converis/portal/Publication/179032396 | |
| dc.date.accessioned | 2025-08-28T02:12:44Z | |
| dc.date.available | 2025-08-28T02:12:44Z | |
| dc.description.abstract | The association between HLA genotypes and type 1 diabetes is well known. We set out to examine incidence rates and ratios of type 1 diabetes depending on the risk afflicted by HLA genotype. Children with the high-risk genotype have a 45-fold disease risk compared to peers with neutral or protective genotypes. | |
| dc.identifier.eissn | 1872-8227 | |
| dc.identifier.jour-issn | 0168-8227 | |
| dc.identifier.olddbid | 208747 | |
| dc.identifier.oldhandle | 10024/191774 | |
| dc.identifier.uri | https://www.utupub.fi/handle/11111/58381 | |
| dc.identifier.url | https://doi.org/10.1016/j.diabres.2023.110256 | |
| dc.identifier.urn | URN:NBN:fi-fe2023032933667 | |
| dc.language.iso | en | |
| dc.okm.affiliatedauthor | Lempainen, Johanna | |
| dc.okm.affiliatedauthor | Ilonen, Jorma | |
| dc.okm.affiliatedauthor | Dataimport, tyks, vsshp | |
| dc.okm.discipline | 3111 Biomedicine | en_GB |
| dc.okm.discipline | 3121 Internal medicine | en_GB |
| dc.okm.discipline | 3123 Gynaecology and paediatrics | en_GB |
| dc.okm.discipline | 3111 Biolääketieteet | fi_FI |
| dc.okm.discipline | 3121 Sisätaudit | fi_FI |
| dc.okm.discipline | 3123 Naisten- ja lastentaudit | fi_FI |
| dc.okm.internationalcopublication | international co-publication | |
| dc.okm.internationality | International publication | |
| dc.okm.type | A1 ScientificArticle | |
| dc.publisher | Elsevier | |
| dc.publisher.country | Ireland | en_GB |
| dc.publisher.country | Irlanti | fi_FI |
| dc.publisher.country-code | IE | |
| dc.relation.articlenumber | 110256 | |
| dc.relation.doi | 10.1016/j.diabres.2023.110256 | |
| dc.relation.ispartofjournal | Diabetes Research and Clinical Practice | |
| dc.relation.volume | 197 | |
| dc.source.identifier | https://www.utupub.fi/handle/10024/191774 | |
| dc.title | Finnish children carrying the high-risk HLA genotype have a 45-fold increased risk of type 1 diabetes compared to peers with neutral or protective genotypes | |
| dc.year.issued | 2023 |
Tiedostot
1 - 1 / 1
Ladataan...
- Name:
- 1-s2.0-S0168822723000219-main.pdf
- Size:
- 345.18 KB
- Format:
- Adobe Portable Document Format